EC Number   |
General Information |
Reference |
|---|
    1.4.3.22 | evolution |
high evolutionary conservation of all four glycosylation sites |
765044 |
| 1.4.3.22 | malfunction |
the serum diamine oxidase is responsible for the symptoms of histamine intolerance |
763860 |
| 1.4.3.22 | metabolism |
diamine oxidase is one of the key enzymes for gamma-aminobutyric acid formation |
725810 |
| 1.4.3.22 | metabolism |
hDAO is the frontline enzyme for histamine metabolism |
710740 |
| 1.4.3.22 | metabolism |
the enzyme is involved in histamine metabolism |
765044 |
| 1.4.3.22 | more |
a simple and sensitive fluorescence assay is described to measure diamine oxidase activity in complex matrices like plasma or tissue extracts using the natural diamine oxidase substrates cadaverine and putrescine |
764833 |
| 1.4.3.22 | physiological function |
main enzyme responsible for histamine degradation in the extracellular matrix |
763860 |
| 1.4.3.22 | physiological function |
root cultures of Hyoscyamus niger produce nicotine and tropane alkaloids by the same early biosynthetic pathway in which the DAO functions to convert N-methylputrescine to methylpyrrolinium cation. There is no close correlaion between alkaloid production and DAO activity. The biosynthesis of nicotine and tropane alkaloids are not regulated directly by the DAO activities. Specificty for N-methylated diamines enable the Hyoscyamine enzyme to function specifically in tropane alkaloid biosynthesis |
720756 |
| 1.4.3.22 | physiological function |
study of the enzymes of N-alkyltropane biosynthesis: tropinone reductase I (EC 1.1.1.206), tropinone reductase II (EC 1.1.1.236), and tropin:acyl-CoA transferase, pseudotropine:acyl-CoA transferase |
347973 |
| 1.4.3.22 | physiological function |
the enzyme is a major source of aluminium-induced peroxide accumulation in the nodules |
743259 |
