EC Number   |
Expression |
Reference |
|---|
    1.3.1.72 | up |
activation of constitutive androstane receptor (CAR) in cultured human hepatocytes increases mRNA levels of mouse Dhcr24 and human DHCR24. A CAR-responsive element is identified in the promoter of human DHCR24 |
726516 |
| 1.3.1.72 | up |
activation of constitutive androstane receptor (CAR) in mouse livers increases mRNA levels of mouse Dhcr24 and human DHCR24 |
726516 |
| 1.3.1.72 | up |
DHCR24 is overexpressed in hepatitis C virus-related hepatocellular carcinoma specifically induced by hepatitis C virus |
746181 |
| 1.3.1.72 | more |
DHCR24 is transcriptionally regulated by sterols via the sterol-regulatory element-binding protein-2 transcription factor |
745512 |
| 1.3.1.72 | down |
enzyme expression is down-regulated by application of castasterone and brassinolide |
765153 |
| 1.3.1.72 | up |
enzyme mRNA expression level is significantly increased in protein disulfide isomerase A3 siRNA-treated neurons |
764825 |
| 1.3.1.72 | more |
expression of DHCR24 is mediated by two sterol regulatory elements (SREs) in the promoter of the gene, assisted by two nearby NF-Y binding sites |
724443 |
| 1.3.1.72 | up |
hepatitis C virus induces the DHCR24 overexpression in human hepatocytes |
712405 |
| 1.3.1.72 | down |
histone acetylation also regulates DHCR24 expression, with a reduction in DHCR24 transcription correlating with recruitment of acetylated histones H3 and H4 to its promoter |
746354 |
| 1.3.1.72 | more |
the enzyme is regulated by the following transcription factors/proteins: sterol regulatory element binding protein 2, nuclear factor Y (via methylation), specificity protein 1, estrogen receptor, androgen receptor, thyroid hormone receptor, constitutive androstane receptor, and pregnane X receptor. Transcriptional regulation of DHCR24, detailed overview |
746354 |
