Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.3.1.72 extracted from

  • Youn, J.H.; Kim, T.W.; Joo, S.H.; Son, S.H.; Roh, J.; Kim, S.; Kim, T.W.; Kim, S.K.
    Function and molecular regulation of DWARF1 as a C-24 reductase in brassinosteroid biosynthesis in Arabidopsis (2018), J. Exp. Bot., 69, 1873-1886 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
24-methylenecholesterol + NADPH + H+
-
Arabidopsis thaliana campesterol + NADP+
-
?
additional information the enzyme has enzyme activity not only for a sterol C-24 reductase, but also for a brassinosteroid C-24 reductase that catalyzes C-24 reduction of 6-deoxodolichosterone to 6-deoxocastasterone and of dolichosterone to castasterone in Arabidopsis thaliana Arabidopsis thaliana ?
-
-

Synonyms

Synonyms Comment Organism
DWARF1
-
Arabidopsis thaliana
DWF1
-
Arabidopsis thaliana
sterol C-24 reductase
-
Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana enzyme expression is down-regulated by application of castasterone and brassinolide down

General Information

General Information Comment Organism
metabolism biosynthesis of 24-methylene brassinosteroid is an alternative route for generating castasterone, which is mediated and regulated by the enzyme in Arabidopsis thaliana Arabidopsis thaliana
physiological function the enzyme functions in biosynthesis of active brassinosteroids in Arabidopsis thaliana. Enzyme overexpression enhances growth and development in Arabidopsis Arabidopsis thaliana