EC Number |
Metals/Ions |
Reference |
---|
6.2.1.1 | Ca2+ |
10 mM, can replace Mg2+ in activation, with 30% of the efficiency relative to Mg2+ |
553 |
6.2.1.1 | Mn2+ |
10 mM, 90% of the activation relative to Mg2+ |
553 |
6.2.1.1 | Mg2+ |
Km: 4.0 mM |
554, 559 |
6.2.1.1 | Mg2+ |
required |
553, 554, 559, 560, 563, 568, 574 |
6.2.1.1 | Mn2+ |
10 mM, 38% of the activity relative to Mg2+. Progressive inactivation of the enzyme by MnCl2 is not reversible by subsequent addition of MgCl2 |
554 |
6.2.1.1 | K+ |
absolute requirement for a monovalent cation, stimulates, Km: 14.3 mM, inhibition above 0.1 M |
560 |
6.2.1.1 | Mg2+ |
inhibition above 7 mM |
560 |
6.2.1.1 | Mg2+ |
Km: 0.9 mM |
560 |
6.2.1.1 | Mn2+ |
5 mM, 94% of the activation relative to Mg2+ |
560 |
6.2.1.1 | Na+ |
absolute requirement for a monovalent cation, poor activator, Km: 33 mM, no inhibition at higher concentrations |
560 |