EC Number |
Metals/Ions |
Reference |
---|
4.2.1.2 | Iron |
in cells grown without aeration the Fe-S-independent enzyme form occupies over 80% of the overall fumarase. In aerobically grown cells the Fe-S-dependent fumarase occupies 80% of the overall activity |
33747 |
4.2.1.2 | Iron |
one Fe-S-dependent enzyme form and one Fe-S-independent enzyme form |
33747, 33768 |
4.2.1.2 | Iron |
fumarase A contains a catalytically active [4Fe-4S]cluster |
33770 |
4.2.1.2 | Mg2+ |
2 mM, slight stimulation |
678771 |
4.2.1.2 | Fe |
enzyme contains an oxygen-sensitive [4Fe-4S] cluster |
679910 |
4.2.1.2 | more |
aluminium and gallium do not perturb the activity of fumarase C |
695741 |
4.2.1.2 | Ca2+ |
has a small stimulatory effect |
715093 |
4.2.1.2 | more |
no effects of Zn2+, Fe2+, or EDTA on enzyme activity |
715093 |
4.2.1.2 | Mg2+ |
required, stimulates 10% at 5 mM |
716122 |
4.2.1.2 | more |
class II fumarase activity is frequently influenced by divalent metal ions and non-ionic surfactants. No effect by Ca2+ |
716122 |