EC Number   |
Metals/Ions |
Reference |
|---|
    4.2.1.2 | [3Fe-4S] center |
10-25% of purified protein contains [3Fe-4S] cluster |
730721 |
| 4.2.1.2 | Mg2+ |
10fold activation of isoform Fum2 |
749006 |
| 4.2.1.2 | Mn2+ |
15fold activation of isoform Fum2 |
749006 |
| 4.2.1.2 | Mg2+ |
2 mM, slight stimulation |
678771 |
| 4.2.1.2 | Mg2+ |
about 20fold activation of isoform Fum1 |
749006 |
| 4.2.1.2 | more |
activity does not increase upon incubation with Fe2+ |
749072 |
| 4.2.1.2 | Fe2+ |
aerobic purification results in inactive protein, which can only partly be reactivated with Fe2+ and thiol |
749072 |
| 4.2.1.2 | more |
aluminium and gallium do not perturb the activity of fumarase C |
695741 |
| 4.2.1.2 | more |
class II fumarase activity is frequently influenced by divalent metal ions and non-ionic surfactants. No effect by Ca2+ |
716122 |
| 4.2.1.2 | Mn2+ |
cytosolic form gets strongly activated, mitochondrial form only less effectively activated |
730558 |
