EC Number |
Metals/Ions |
Reference |
---|
5.1.99.1 | Co2+ |
most potent activator, Km: 0.0002 mM, binds 2 mol Co2+ per mol of racemase |
2434 |
5.1.99.1 | Mn2+ |
increases activity to a smaller extent than Co2+ |
2437 |
5.1.99.1 | more |
enzyme does not require tightly bound metal ions for activity, they are not released even after extensive dialysis at pH 2.4 |
2437 |
5.1.99.1 | Ni2+ |
increases activity to a smaller extent than Co2+ |
2437 |
5.1.99.1 | Zn2+ |
increases activity to a smaller extent than Co2+ |
2437 |
5.1.99.1 | Co2+ |
increases activity |
2437, 2442 |
5.1.99.1 | Co3+ |
lower level of activation than Co2+ at higher concentrations |
2442 |
5.1.99.1 | Fe2+ |
lower level of activation than Co2+ at higher concentrations |
2442 |
5.1.99.1 | Mn2+ |
lower level of activation than Co2+ at higher concentrations |
2442 |
5.1.99.1 | more |
His12, Gln65, His91 and Glu141 provide a binding site for a divalent metal ion, as shown by binding of Co2+ |
653930 |