EC Number   |
Inhibitors |
Structure |
|---|
    1.2.1.59 | 3-phospho-D-glyceroyl phosphate |
- |
   |
| 1.2.1.59 | ATP |
activates NADP+-dependent activity, inhibits NAD+-dependent activity |
|
| 1.2.1.59 | D-glyceraldehyde 3-phosphate |
- |
|
| 1.2.1.59 | GuHCl |
the enzyme retains more than 50% activity after 72 h of incubation in the presence of 4 M GuHCl, and 15% at 6 M GuHCl |
|
| 1.2.1.59 | more |
insensitive to pentalenolactone |
|
| 1.2.1.59 | more |
no influence on activity is observed on assaying of the enzyme with 5 mM substrate and 0.5 mM co-substrate with 1 mM ATP, ADP, AMP, glucose 6-phosphate, fructose 6-phosphate, galactose 1-phosphate, glucose 1-phosphate or coenzyme A in either the glycolytic or gluconeogenic reaction |
|
| 1.2.1.59 | more |
a dramatic accumulation of NADH and NADPH is observed when ethanol is added to the culture. The Gapdh from Thermoanaerobacterium saccharolyticum is less sensitive to the NADH/NAD+ ratio |
|
| 1.2.1.59 | NAD+ |
- |
|
| 1.2.1.59 | NADH |
- |
|
| 1.2.1.59 | NADP+ |
- |
|
