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Information on EC 1.2.1.59 - glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)

for references in articles please use BRENDA:EC1.2.1.59

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IUBMB Comments

NAD+ and NADP+ can be used as cofactors with similar efficiency, unlike EC 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) and EC 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating), which are NAD+- and NADP+-dependent, respectively.

The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota

Synonyms
gapdh, glyceraldehyde-3-phosphate dehydrogenase, glyceraldehyde 3-phosphate dehydrogenase, chloroplast glyceraldehyde-3-phosphate dehydrogenase, nadp-dependent glyceraldehyde-3-phosphate dehydrogenase, gapdh2, phosphorylating glyceraldehyde-3-phosphate dehydrogenase, gbs gapdh, nadp-dependent glyceraldehydephosphate dehydrogenase, nadp-dependent glyceraldehyde 3-phosphate dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+
show the reaction diagram