EC Number   |
Inhibitors |
Structure |
|---|
   3.2.1.62 | conduritol-B-epoxide |
90% inactivation of lactase hydrolysis, 55% inactivation of phlorizin hydrolysis, inactivation by covalent binding to Glu1747 and Glu 1271 |
   |
| 3.2.1.62 | Cu2+ |
about 10% residual activity at 1 mM |
|
| 3.2.1.62 | D-galactal |
inactivation of lactase hydrolase activity |
|
| 3.2.1.62 | D-galactono-1,4-lactone |
competitive inhibition of lactase activity, Ki: 0.35 mM |
|
| 3.2.1.62 | D-galactono-1,4-lactone |
competitive inhibition of lactase activity, not phlorizin activity, Ki: 2 mM |
|
| 3.2.1.62 | D-glucal |
inactivation of lactase hydrolase activity |
|
| 3.2.1.62 | D-glucono-1,5-lactone |
competitive inhibition of lactase activity, Ki: 0.027 mM |
|
| 3.2.1.62 | D-glucono-1,5-lactone |
competitive inhibition of phlorizin hydrolysis, Ki: 0.18 mM, competitive inhibition of lactase activity, Ki: 0.275 mM |
|
| 3.2.1.62 | D-glucose |
- |
|
| 3.2.1.62 | deoxygalactonojirimycin |
competitive inhibition, Ki: 0.076 mM |
|
