EC Number   |
Activating Compound |
Reference |
|---|
   7.5.2.6 | 3-deoxy-D-mannooctulosonic acid (Kdo)2-lipid A |
increases the ATPase activity 4-5fold, with half-maximal stimulation at 0.021 mM Kdo2-lipid A, addition of Kdo2-lipid A increases the Vmax and decreases the Km. The stimulation is only seen with hexaacylated lipid A species and not with precursors, such as diacylated lipid X or tetraacylated lipid IVA |
751011 |
| 7.5.2.6 | hexaacylated lipid A |
is an especially potent activator |
751011 |
| 7.5.2.6 | Lipid |
from Escherichia coli, about 1.4fold stimulation |
698746 |
| 7.5.2.6 | lipid A |
about 2fold stimulation of the ATPase activity of MsbA by its substrate |
698746 |
| 7.5.2.6 | more |
activity of MsbA can be selectively stimulated by different truncated versions of core oligosaccharides of Pseudomonas aeruginosa lipopolysaccharide (LPS). Phosphate substituents in the lipid A-core are important for stimulating ATPase activity of MsbA |
751020 |
| 7.5.2.6 | more |
activity shown to be selectively stimulated by different truncated versions of core oligosaccharides of lipopoysaccharides of Pseudomonas aeruginosa |
687605 |
| 7.5.2.6 | phosphocholine |
2fold stimulation of MsbA |
698746 |
| 7.5.2.6 | Phospholipids |
stimulate the ATPase activity of the purified enzyme |
751011 |
| 7.5.2.6 | taxol |
1.4fold stimulation of the wild-type enzyme, no stimulation of mutant S289A/S290A. Erythromycin resistance is conferred by wild-type or mutant MsbA, taxol is sufficient to reverse the erythromycin resistance of wild-type MsbA-expressing cells |
696222 |
