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EC Number	Activating Compound	Commentary	Reference
2.8.4.1	Ti(III) citrate	-	393255, 393256
2.8.4.1	Ti(III) citrate	activation of the oxidized state of enzyme	393246
2.8.4.1	Ti(III) citrate	artificial electron donor, if used as electron source component A1 is no longer required	393257
2.8.4.1	Ti(III) citrate	conversion from the ox1 to the red1 state, maximal activation after 30 min, 20 mM Ti(III) at pH 9.0 and room temperature or pH 7.0 and 60°C, optimal pH for activation of isoenzyme II is 10.0, enzyme is activated when the enzyme bound coenzyme F-430 is reduced to the Ni(I) state	393247
2.8.4.1	Ti(III) citrate	nickel tetrahydrocorphin	393258
2.8.4.1	Ti(III) citrate	prevents enzyme inactivation by oxygen	393252
2.8.4.1	Ti(III) citrate	reactivation after isolation	393251
2.8.4.1	vitamin B12	enzyme system is stimulated	393257

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Release 2023.1 (January 2023)