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Gene ontology
Version 2014-12-22
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Details for positive regulation of hh target transcription factor activity
Gene ontology ID
GO:0007228
Definition
Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited
Synonyms
1. activation of hh target transcription factor
2. positive regulation of hedgehog target transcription factor
References
1. GOC: dph
2. GOC: tb
3. PMID 11912487
4. PMID 15057936
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