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Gene ontology
Version 2014-12-22
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Details for mitochondrial outer membrane permeabilization
Gene ontology ID
GO:0097345
Definition
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway
Comment
BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively).
Synonyms
1. mitochondrial outer membrane permeabilization
2. mitochondrial outer membrane permeabilization during apoptotic cell death
3. MOMP
References
1. GOC: BHF
2. GOC: mtg apoptosis
3. GOC: pg
4. PMID 21041309
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