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Gene ontology
Version 2014-12-22
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Details for phosphorylation of RNA polymerase II C-terminal domain serine 2 residues
Gene ontology ID
GO:0071619
Definition
The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans
References
1. GOC: krc
2. PMID 17079683
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