Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 7.2.4.2 - oxaloacetate decarboxylase (Na+ extruding)

for references in articles please use BRENDA:EC7.2.4.2

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

The enzyme from the bacterium Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA. The process is accompanied by the extrusion of two sodium ions from cells. Some animal enzymes require Mn2+. Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na+ transport.

The enzyme appears in viruses and cellular organisms

Synonyms
EC 4.1.1.3, Oad-alpha, oxaloacetate decarboxylase primary Na+ pump, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
oxaloacetate + 2 Na+[side 1] = pyruvate + CO2 + 2 Na+[side 2]
show the reaction diagram
-
-
-
-
oxaloacetate = pyruvate + CO2
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
Highest Expressing Human Cell Lines
Cell Line Links Gene Links