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Adenocarcinoma of Lung
Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2?-mediated tumor progression.
Alzheimer Disease
MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.
Alzheimer Disease
Synaptosomal proteins, beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma-SNAP and synaptotagmin I in brain of patients with Down syndrome and Alzheimer's disease.
Amyotrophic Lateral Sclerosis
An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication.
Amyotrophic Lateral Sclerosis
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.
Apraxias
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.
Arthritis, Rheumatoid
AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts.
Asthma
ATP6V0d2 Suppresses Alveoli Macrophage Alternative Polarization and Allergic Asthma via Degradation of PU.1.
Ataxia
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.
Bacterial Infections
Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis.
Bacterial Infections
The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion.
Bone Resorption
(-)-Epigallocatechin-3-gallate inhibits RANKL-induced osteoclastogenesis via downregulation of NFATc1 and suppression of HO-1-HMGB1-RAGE pathway.
Bone Resorption
ASP2-1, a polysaccharide from Acorus tatarinowii Schott, inhibits osteoclastogenesis via modulation of NFATc1 and attenuates LPS-induced bone loss in mice.
Bone Resorption
Atp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption.
Bone Resorption
Combined Extracts of Herba Epimedii and Fructus Ligustri Lucidi Rebalance Bone Remodeling in Ovariectomized Rats.
Bone Resorption
Disulfiram attenuates osteoclast differentiation in vitro: a potential antiresorptive agent.
Bone Resorption
LncRNA Bmncr alleviates the progression of osteoporosis by inhibiting RANML-induced osteoclast differentiation.
Bone Resorption
Nirogacestat suppresses RANKL-Induced osteoclast formation in vitro and attenuates LPS-Induced bone resorption in vivo.
Bone Resorption
Osteocytes Acidify Their Microenvironment in Response to PTHrP In Vitro and in Lactating Mice In Vivo.
Bone Resorption
Tenuigenin inhibits RANKL-induced osteoclastogenesis by down-regulating NF-?B activation and suppresses bone loss in vivo.
Botulism
A yeast assay probes the interaction between botulinum neurotoxin serotype B and its SNARE substrate.
Botulism
Botulinum and Tetanus Neurotoxin-Induced Blockade of Synaptic Transmission in Networked Cultures of Human and Rodent Neurons.
Botulism
Novel Native and Engineered Botulinum Neurotoxins.
Botulism
Peptide inhibitors of botulinum neurotoxin serotype A: design, inhibition, cocrystal structures, structure-activity relationship and pharmacophore modeling.
Botulism
Targeting the epithelial SNARE machinery by bacterial neurotoxins.
Brain Diseases
MUNC18-1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development.
Brain Injuries, Traumatic
Traumatic Brain Injury Impairs Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor Complex Formation and Alters Synaptic Vesicle Distribution in the Hippocampus.
Brain Ischemia
Dysfunction of Membrane Trafficking Leads to Ischemia-Reperfusion Injury After Transient Cerebral Ischemia.
Brain Ischemia
Identification of differentially expressed proteins and validation of the changes of N-ethylmaleimide-sensitive factor in rats with focal cerebral ischemia after transection of the cervical sympathetic trunk.
Brain Ischemia
Inactivation of NSF ATPase Leads to Cathepsin B Release After Transient Cerebral Ischemia.
Brain Ischemia
Interruption of endolysosomal trafficking leads to stroke brain injury.
Breast Neoplasms
The oncogenic role of TRIP13 in regulating proliferation, invasion, and cell cycle checkpoint in NSCLC cells.
Carcinogenesis
ATP6V0D2, a subunit associated with proton transport, serves an oncogenic role in esophagus cancer and is correlated with epithelial-mesenchymal transition.
Carcinoma
Elevated expression of the V-ATPase D2 subunit triggers increased energy metabolite levels in KrasG12D -driven cancer cells.
Carcinoma, Hepatocellular
Silencing of Taxol-Sensitizer Genes in Cancer Cells: Lack of Sensitization Effects.
Cholera
Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate.
Ciliopathies
Comparative Proteomics Reveals Timely Transport into Cilia of Regulators or Effectors as a Mechanism Underlying Ciliary Disassembly.
Ciliopathies
Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.
Colitis
The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion.
Colonic Neoplasms
Degradation of tyrosine phosphatase PTPN3 (PTPH1) by association with oncogenic human papillomavirus E6 proteins.
Colorectal Neoplasms
TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status.
Coma
Analysis of NSF mutants reveals residues involved in SNAP binding and ATPase stimulation.
Coma
Analysis of the mutant Drosophila N-ethylmaleimide sensitive fusion-1 protein in comatose reveals molecular correlates of the behavioural paralysis.
Coma
Dominant-negative NSF2 disrupts the structure and function of Drosophila neuromuscular synapses.
Coma
Genetic Modifiers of comatose Mutations in Drosophila: Insights Into Neuronal NSF (N-Ethylmaleimide-Sensitive Fusion Factor) Functions.
Coma
Genetic modifiers of the Drosophila NSF mutant, comatose, include a temperature-sensitive paralytic allele of the calcium channel alpha1-subunit gene, cacophony.
Coma
Synaptic physiology and ultrastructure in comatose mutants define an in vivo role for NSF in neurotransmitter release.
Coma
The Drosophila NSF protein, dNSF1, plays a similar role at neuromuscular and some central synapses.
Coma
The ubiquitin ligase Ariadne-1 regulates neurotransmitter release via ubiquitination of NSF.
Coronary Disease
Microarray profiling analysis and validation of novel long noncoding RNAs and mRNAs as potential biomarkers and their functions in atherosclerosis.
Cutis Laxa
Expanding the clinical and genetic heterogeneity of hereditary disorders of connective tissue.
Cystic Fibrosis
Calcium and sodium transport processes in patients with cystic fibrosis. I. A specific decrease in Mg2+-dependent, Ca2+-adenosine triphosphatase activity in erythrocyte membranes from cystic fibrosis patients.
Cystic Fibrosis
Calcium-ATPase activity in cystic fibrosis erythrocyte membranes: decreased activity in patients with pancreatic insufficiency.
Cystic Fibrosis
Cystic fibrosis transmembrane conductance regulator degradation depends on the lectins Htm1p/EDEM and the Cdc48 protein complex in yeast.
Cystic Fibrosis
The Cystic Fibrosis Transmembrane Conductance Regulator's Expanding SNARE Interactome.
Cystic Fibrosis
VCP/p97 AAA-ATPase does not interact with the endogenous wild-type cystic fibrosis transmembrane conductance regulator.
Cysts
A proteomic study on postdiapaused embryonic development of brine shrimp (Artemia franciscana).
Dementia
Accumulation of ?-synuclein triggered by presynaptic dysfunction.
dermatan 4-sulfotransferase deficiency
Impaired Cognitive Function and Altered Hippocampal Synaptic Plasticity in Mice Lacking Dermatan Sulfotransferase Chst14/D4st1.
Dermatitis, Atopic
Role of SNAREs in Atopic Dermatitis-Related Cytokine Secretion and Skin-Nerve Communication.
Diabetes Mellitus, Type 2
Effect of glucolipotoxicity and rosiglitazone upon insulin secretion.
Down Syndrome
Synaptosomal proteins, beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma-SNAP and synaptotagmin I in brain of patients with Down syndrome and Alzheimer's disease.
Dystonia
Functional evidence implicating a novel TOR1A mutation in idiopathic, late-onset focal dystonia.
Dystonia
Torsin mediates primary envelopment of large ribonucleoprotein granules at the nuclear envelope.
Dystonic Disorders
The Dystonia-associated Protein TorsinA Modulates Synaptic Vesicle Recycling.
Epilepsy
A novel NAPB splicing mutation identified by Trio-based exome sequencing is associated with early-onset epileptic encephalopathy.
Epilepsy
ATPase N-ethylmaleimide-sensitive Fusion Protein: A Novel Key Player for Causing Spontaneous Network Excitation in Human Temporal Lobe Epilepsy.
Epilepsy, Temporal Lobe
ATPase N-ethylmaleimide-sensitive Fusion Protein: A Novel Key Player for Causing Spontaneous Network Excitation in Human Temporal Lobe Epilepsy.
Esophageal Neoplasms
ATP6V0D2, a subunit associated with proton transport, serves an oncogenic role in esophagus cancer and is correlated with epithelial-mesenchymal transition.
Exocrine Pancreatic Insufficiency
Calcium-ATPase activity in cystic fibrosis erythrocyte membranes: decreased activity in patients with pancreatic insufficiency.
Frontotemporal Dementia
Mutant valosin-containing protein causes a novel type of frontotemporal dementia.
Frontotemporal Dementia
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations.
Frontotemporal Dementia
p97-containing complexes in proliferation control and cancer: emerging culprits or guilt by association?
Frontotemporal Dementia
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.
Frontotemporal Dementia
Syntaxin 13, a Genetic Modifier of Mutant CHMP2B in Frontotemporal Dementia, Is Required for Autophagosome Maturation.
Glaucoma
Ectopic vesicular glutamate release at the optic nerve head and axon loss in mouse experimental glaucoma.
Granulomatous Disease, Chronic
The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion.
Heart Defects, Congenital
Characterization of soluble N-ethylmaleimide-sensitive factor attachment protein receptor gene STX18 variations for possible roles in congenital heart diseases.
Hematologic Neoplasms
TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma.
Hydrocephalus
Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia.
Hydrocephalus
Heterogeneous expression of hydrocephalic phenotype in the hyh mice carrying a point mutation in alpha-SNAP.
Hydrocephalus
Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.
Hydrocephalus
The gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) mice.
Hypertension
Depletion of the ATPase NSF from Golgi membranes with hypo-S-nitrosylation of vasorelevant proteins in endothelial cells exposed to monocrotaline pyrrole.
Hypotension
Inactivation of NSF ATPase Leads to Cathepsin B Release After Transient Cerebral Ischemia.
Hypothyroidism
Effect of hypothyroidism on ionic metabolism and Na-K activated ATP phosphohydrolase activity in the developing rat brain.
Hypothyroidism
Effect of Thyroxine on SNARE Complex and Synaptotagmin-1 Expression in the Prefrontal Cortex of Rats with Adult-onset Hypothyroidism.
Infarction, Middle Cerebral Artery
NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke.
Infections
A non-envelopment role for the ESCRT-III complex during HCMV infection.
Infections
A role for the SNARE protein syntaxin 3 in human cytomegalovirus morphogenesis.
Infections
Blocking the expression of syntaxin 4 interferes with initial phagocytosis of Brucella melitensis in macrophages.
Infections
CDC48 function during TMV infection: Regulation of virus movement and replication by degradation?
Infections
Coat Protein Complex I Facilitates Dengue Virus Production.
Infections
Colletotrichum orbiculare FAM1 Encodes a Novel Woronin Body-Associated Pex22 Peroxin Required for Appressorium-Mediated Plant Infection.
Infections
Control of Tobacco mosaic virus movement protein fate by CELL-DIVISION-CYCLE protein48.
Infections
Soluble N-ethylmaleimide-sensitive factor attachment protein receptors required during Trypanosoma cruzi parasitophorous vacuole development.
Infections
Subversion of NPC1 pathway of cholesterol transport by Anaplasma phagocytophilum.
Infections
The Autophagy Protein ATG16L1 Is Required for Sindbis Virus-Induced eIF2? Phosphorylation and Stress Granule Formation.
Infections
The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection.
Influenza, Human
Drosophila RNAi screen identifies host genes important for influenza virus replication.
Ischemic Attack, Transient
Correction to: Inactivation of NSF ATPase Leads to Cathepsin B Release After Transient Cerebral Ischemia.
Ischemic Attack, Transient
Inactivation of NSF ATPase Leads to Cathepsin B Release After Transient Cerebral Ischemia.
Ischemic Stroke
NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke.
Kidney Neoplasms
Expression of acidosis-dependent genes in human cancer nests.
Leukemia
An Immunohistochemical Survey of SNARE Proteins Shows Distinct Patterns of Expression in Hematolymphoid Neoplasia.
Liposarcoma
Cysteine Modifications in the Pathogenesis of ALS.
Lung Neoplasms
Next generation sequencing analysis of lung cancer datasets: A functional genomics perspective.
Lymphoma
An Immunohistochemical Survey of SNARE Proteins Shows Distinct Patterns of Expression in Hematolymphoid Neoplasia.
Malaria
A homologue of N-ethylmaleimide-sensitive factor in the malaria parasite Plasmodium falciparum is exported and localized in vesicular structures in the cytoplasm of infected erythrocytes in the brefeldin A-sensitive pathway.
Malnutrition
Effect of exercise during rehabilitation on swimming performance, metabolism and function of muscle in rats.
Melanoma
Elevated expression of the V-ATPase D2 subunit triggers increased energy metabolite levels in KrasG12D -driven cancer cells.
Melanoma
The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion.
Metabolic Diseases
A novel role of peroxin PEX6: suppression of aging defects in mitochondria.
Mitochondrial Diseases
A novel role of peroxin PEX6: suppression of aging defects in mitochondria.
Multiple Myeloma
A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Multiple Myeloma
TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma.
Muscle Spasticity
Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis.
Muscular Atrophy, Spinal
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.
Muscular Diseases
A conserved inter-domain communication mechanism regulates the ATPase activity of the AAA-protein Drg1.
Muscular Diseases
Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast.
Muscular Diseases
Mutant valosin-containing protein causes a novel type of frontotemporal dementia.
Muscular Diseases
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations.
Muscular Diseases
p97-containing complexes in proliferation control and cancer: emerging culprits or guilt by association?
Myocardial Infarction
N-ethylmaleimide-sensitive factor siRNA improves cardiac function following myocardial infarction in rats.
Neoplasm Metastasis
TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status.
Neoplasm Metastasis
VAMP8, a vesicle-SNARE required for RAB37-mediated exocytosis, possesses a tumor metastasis suppressor function.
Neoplasms
A novel function of AAA-ATPase p97/VCP in the regulation of cell motility.
Neoplasms
Bi-allelic Missense Pathogenic Variants in TRIP13 Cause Female Infertility Characterized by Oocyte Maturation Arrest.
Neoplasms
Elevated expression of the V-ATPase D2 subunit triggers increased energy metabolite levels in KrasG12D -driven cancer cells.
Neoplasms
High expression of YKT6 associated with progression and poor prognosis of hepatocellular carcinoma.
Neoplasms
Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2?-mediated tumor progression.
Neoplasms
Maintenance of nucleosomal balance in cis by conserved AAA-ATPase Yta7.
Neoplasms
Non-bone metastatic cancers promote osteocyte-induced bone destruction.
Neoplasms
Observation of a Transient Reaction Intermediate Illuminates the Mechanochemical Cycle of the AAA-ATPase p97.
Neoplasms
Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse.
Neoplasms
Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy.
Neoplasms
R-SNARE ykt6 resides in membrane-associated protease-resistant protein particles and modulates cell cycle progression when over-expressed.
Neoplasms
Significance of Vesicle-Associated Membrane Protein 8 Expression in Predicting Survival in Breast Cancer.
Neoplasms
Silencing of Taxol-Sensitizer Genes in Cancer Cells: Lack of Sensitization Effects.
Neoplasms
SNAP-23 and VAMP-3 contribute to the release of IL-6 and TNF? from a human synovial sarcoma cell line.
Neoplasms
Targeting SNARE-Mediated Vesicle Transport to Block Invadopodium-Based Cancer Cell Invasion.
Neoplasms
The common occurrence of ATP diphosphohydrolase in mammalian plasma membranes.
Neoplasms
The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion.
Neoplasms
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
Neoplasms
TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status.
Neoplasms
Up-regulation expression and prognostic significance of Syntaxin4 in kidney renal clear cell carcinoma.
Neoplasms
VAMP8, a vesicle-SNARE required for RAB37-mediated exocytosis, possesses a tumor metastasis suppressor function.
Neoplasms
VCP/p97 targets the nuclear export and degradation of p27Kip1 during G1 to S phase transition.
Neuroblastoma
Malignant rhabdoid tumor shows incomplete neural characteristics as revealed by expression of SNARE complex.
Neurodegenerative Diseases
Microarray analysis of differentially expressed genes in vaginal tissues in postmenopausal women. The role of stress urinary incontinence.
Ocular Hypertension
Ectopic vesicular glutamate release at the optic nerve head and axon loss in mouse experimental glaucoma.
Osteitis Deformans
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations.
Osteochondrosis
Identification of novel osteochondrosis- Associated genes.
Osteolysis
Non-bone metastatic cancers promote osteocyte-induced bone destruction.
Ovarian Neoplasms
Silencing of Taxol-Sensitizer Genes in Cancer Cells: Lack of Sensitization Effects.
Pancreatitis, Alcoholic
Susceptibility Factors and Cellular Mechanisms Underlying Alcoholic Pancreatitis.
Paralysis
A yeast assay probes the interaction between botulinum neurotoxin serotype B and its SNARE substrate.
Paralysis
Development of cell-based assays to measure botulinum neurotoxin serotype A activity using cleavage-sensitive antibodies.
Paralysis
Molecular structures and functional relationships in clostridial neurotoxins.
Paralysis
Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis.
Paralysis
Novel Native and Engineered Botulinum Neurotoxins.
Paralysis
Peptide inhibitors of botulinum neurotoxin serotype A: design, inhibition, cocrystal structures, structure-activity relationship and pharmacophore modeling.
Paralysis
Structure- and substrate-based inhibitor design for Clostridium botulinum neurotoxin serotype A.
Paralysis
STX6 rs1411478 is not associated with increased risk of Parkinson's disease.
Parkinson Disease
SNAP25 Gene Polymorphisms Protect Against Parkinson's Disease and Modulate Disease Severity in Patients.
Peritonitis
A novel inhibitor of N-ethylmaleimide-sensitive factor decreases leukocyte trafficking and peritonitis.
Prion Diseases
Downregulation of ?-Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein: Proteomics-Based Identification in Early-Stage Prion Disease.
Prostatic Neoplasms
The oncogenic role of TRIP13 in regulating proliferation, invasion, and cell cycle checkpoint in NSCLC cells.
Pulmonary Arterial Hypertension
Depletion of the ATPase NSF from Golgi membranes with hypo-S-nitrosylation of vasorelevant proteins in endothelial cells exposed to monocrotaline pyrrole.
Reperfusion Injury
Inhibiting ATP6V0D2 Aggravates Liver Ischemia-Reperfusion Injury by Promoting NLRP3 Activation via Impairing Autophagic Flux Independent of Notch1/Hes1.
Retinal Dystrophies
Expanding the clinical and genetic spectrum of Heimler syndrome.
Rhabdoid Tumor
Malignant rhabdoid tumor shows incomplete neural characteristics as revealed by expression of SNARE complex.
Sarcoma
Induction of sarcomas in athymic mice.
Sarcoma
Next generation sequencing analysis of lung cancer datasets: A functional genomics perspective.
Sarcoma, Synovial
SNAP-23 and VAMP-3 contribute to the release of IL-6 and TNF? from a human synovial sarcoma cell line.
Seizures
Abnormal expression of epilepsy-related gene ERG1/NSF in the spontaneous recurrent seizure rats with spatial learning memory deficits induced by kainic acid.
Seizures
Effects of spontaneous recurrent seizures on cognitive function via modulation of SNAREs expression.
Sepsis
[Suppressive effect of CORM-2 on platelet ?-granule exocytosis in sepsis via SNARE/Munc18b complex formation].
Spinocerebellar Ataxias
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.
Starvation
The Machado-Joseph disease deubiquitylase ataxin-3 interacts with LC3C/GABARAP and promotes autophagy.
Stomach Neoplasms
Expression of acidosis-dependent genes in human cancer nests.
Supranuclear Palsy, Progressive
STX6 rs1411478 is not associated with increased risk of Parkinson's disease.
Tetanus
A role for synaptotagmin VII-regulated exocytosis of lysosomes in neurite outgrowth from primary sympathetic neurons.
Tetanus
Botulinum and Tetanus Neurotoxin-Induced Blockade of Synaptic Transmission in Networked Cultures of Human and Rodent Neurons.
Tetanus
Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy.
Tetanus
Inhibition of SNARE-mediated membrane traffic impairs cell migration.
Tetanus
Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: role of TI-VAMP.
Tetanus
Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses.
Tetanus
Minimum essential factors required for vesicle mobilization at hippocampal synapses.
Tetanus
Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis.
Tetanus
Preparation of Cerebellum Granule Neurons from Mouse or Rat Pups and Evaluation of Clostridial Neurotoxin Activity and Their Inhibitors by Western Blot and Immunohistochemistry.
Tetanus
Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth.
Tetanus
Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth.
Tetanus
SNARE-mediated trafficking of alpha5beta1 integrin is required for spreading in CHO cells.
Tetanus
Somatodendritic secretion in oxytocin neurons is upregulated during the female reproductive cycle.
Tetanus
Subcellular localization of tetanus neurotoxin-insensitive vesicle-associated membrane protein (VAMP)/VAMP7 in neuronal cells: evidence for a novel membrane compartment.
Tetanus
Substrate recognition mechanism of VAMP/synaptobrevin-cleaving clostridial neurotoxins.
Tetanus
Syntaxin-1/TI-VAMP SNAREs interact with Trk receptors and are required for neurotrophin-dependent outgrowth.
Tetanus
Targeting the epithelial SNARE machinery by bacterial neurotoxins.
Thrombosis
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor.
Tuberculosis
Adenylyl cyclase Rv0386 from Mycobacterium tuberculosis H37Rv uses a novel mode for substrate selection.
Tuberculosis
Deletion of a Mycobacterium tuberculosis proteasomal ATPase homologue gene produces a slow-growing strain that persists in host tissues.
Uterine Cervical Neoplasms
The oncogenic role of TRIP13 in regulating proliferation, invasion, and cell cycle checkpoint in NSCLC cells.
Vaccinia
Drosophila RNAi screen identifies host genes important for influenza virus replication.
vesicle-fusing atpase deficiency
ATP6v0d2 Deficiency Increase Bone Mass, but Does Not Influence Ovariectomy-Induced Bone Loss.
vesicle-fusing atpase deficiency
The Cdc48 Complex Alleviates the Cytotoxicity of Misfolded Proteins by Regulating Ubiquitin Homeostasis.
vesicle-fusing atpase deficiency
v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation.
Vesicular Stomatitis
Differential requirement for N-ethylmaleimide-sensitive factor in endosomal trafficking of transferrin receptor from anterograde trafficking of vesicular stomatitis virus glycoprotein G.
Vesicular Stomatitis
Drosophila RNAi screen identifies host genes important for influenza virus replication.
Vesicular Stomatitis
The ESCRT machinery is not required for human cytomegalovirus envelopment.
Virus Diseases
A non-envelopment role for the ESCRT-III complex during HCMV infection.
Virus Diseases
Drosophila RNAi screen identifies host genes important for influenza virus replication.
Virus Diseases
Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation.
Virus Diseases
The ESCRT machinery is not required for human cytomegalovirus envelopment.
Zellweger Syndrome
A cytoplasmic AAA family peroxin, Pex1p, interacts with Pex6p.
Zellweger Syndrome
Compound heterozygous p. Arg949Trp and p. Gly970Ala mutations deteriorated the function of PEX1p: A study on PEX1 in a patient with Zellweger syndrome.
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Confalonieri, F.; Duguet, M.
A 200-amino acid ATPase module in search of a basic function
Bioessays
17
639-650
1995
Saccharomyces cerevisiae, Candida albicans, Cricetulus longicaudatus, Drosophila melanogaster, Homo sapiens, Mus musculus, Sulfolobus acidocaldarius, Xenopus laevis
brenda
Finken-Eigen, M.; Roehricht, R.A.; Koehrer, K.
The VPS4 gene is involved in protein transport out of a yeast pre-vacuolar endosome-like compartment
Curr. Genet.
31
469-480
1997
Saccharomyces cerevisiae, Homo sapiens, Mus musculus, Schizosaccharomyces pombe
brenda
Babst, M.; Sato, T.K.; Banta, L.M.; Emr, S.D.
Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p
EMBO J.
16
1820-1831
1997
Saccharomyces cerevisiae, Homo sapiens, Mus musculus, Schizosaccharomyces pombe
brenda
Faber, K.N.; Heyman, J.A.; Subramani, S.
Two AAA family peroxins, PpPex1p and PpPex6p, interact with each other in an ATP-dependent manner and are associated with different subcellular membranous structures distinct from peroxisomes
Mol. Cell. Biol.
18
936-943
1998
Homo sapiens, Komagataella pastoris
brenda
Tamura, S.; Shimozawa, N.; Suzuki, Y.; Tsukamoto, T.; Osumi, T.; Fujiki, Y.
A cytoplasmic AAA family peroxin, Pex1p, interacts with Pex6p
Biochem. Biophys. Res. Commun.
245
883-886
1998
Homo sapiens, Rattus norvegicus
brenda
Imamura, A.; Tamura, S.; Shimozawa, N.; Suzuki, Y.; Zhang, Z.; Tsukamoto, T.; Orii, T.; Kondo, N.; Osumi, T.; Fujiki, Y.
Temperature-sensitive mutation in PEX1 moderates the phenotypes of peroxisome deficiency disorders
Hum. Mol. Genet.
7
2089-2094
1998
Homo sapiens
brenda
Yoshimori, T.; Yamagata, F.; Yamamoto, A.; Mizushima, N.; Kabeya, Y.; Nara, A.; Miwako, I.; Ohashi, M.; Ohsumi, M.; Ohsumi, Y.
The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells
Mol. Biol.
11
747-763
2000
Saccharomyces cerevisiae, Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Whiteheart, S.W.; Matveeva, E.A.
Multiple binding proteins suggest diverse functions for the N-ethylmaleimide sensitive factor
J. Struct. Biol.
146
32-43
2004
Homo sapiens
brenda
Tamura, S.; Yasutake, S.; Matsumoto, N.; Fujiki, Y.
Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p
J. Biol. Chem.
281
27693-27704
2006
Homo sapiens
brenda
Platta, H.W.; Debelyy, M.O.; El Magraoui, F.; Erdmann, R.
The AAA peroxins Pex1p and Pex6p function as dislocases for the ubiquitinated peroxisomal import receptor Pex5p
Biochem. Soc. Trans.
36
99-104
2008
Homo sapiens
brenda
Fisher, E.A.; Lapierre, L.R.; Junkins, R.D.; McLeod, R.S.
The AAA-ATPase p97 facilitates degradation of apolipoprotein B by the ubiquitin-proteasome pathway
J. Lipid Res.
49
2149-2160
2008
Homo sapiens
brenda
Naydenov, N.G.; Harris, G.; Brown, B.; Schaefer, K.L.; Das, S.K.; Fisher, P.B.; Ivanov, A.I.
Loss of soluble N-ethylmaleimide-sensitive factor attachment protein alpha (alphaSNAP) induces epithelial cell apoptosis via down-regulation of Bcl-2 expression and disruption of the Golgi
J. Biol. Chem.
287
5928-5941
2012
Homo sapiens
brenda
Caillat, C.; Maity, S.; Miguet, N.; Roos, W.H.; Weissenhorn, W.
The role of VPS4 in ESCRT-III polymer remodeling
Biochem. Soc. Trans.
47
441-448
2019
Homo sapiens
brenda
Rijal, R.; Arhzaouy, K.; Strucksberg, K.; Cross, M.; Hofmann, A.; Schroeder, R.; Clemen, C.; Eichinger, L.
Mutant p97 exhibits species-specific changes of its ATPase activity and compromises the UBXD9-mediated monomerisation of p97 hexamers
Eur. J. Cell Biol.
95
195-207
2016
Homo sapiens (P55072), Homo sapiens, Dictyostelium discoideum (Q75JI3)
brenda
Alonso Y Adell, M.; Migliano, S.M.; Teis, D.
ESCRT-III and Vps4 a dynamic multipurpose tool for membrane budding and scission
FEBS J.
283
3288-3302
2016
Homo sapiens
brenda
Schoeneberg, J.; Pavlin, M.R.; Yan, S.; Righini, M.; Lee, I.H.; Carlson, L.A.; Bahrami, A.H.; Goldman, D.H.; Ren, X.; Hummer, G.; Bustamante, C.; Hurley, J.H.
ATP-dependent force generation and membrane scission by ESCRT-III and Vps4
Science
362
1423-1428
2018
Homo sapiens
brenda
3.6.4.6 vesicle-fusing ATPase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
