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Literature summary for 3.6.4.6 extracted from

  • Tamura, S.; Yasutake, S.; Matsumoto, N.; Fujiki, Y.
    Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p (2006), J. Biol. Chem., 281, 27693-27704.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm Pex1p possesses two distinct oligomeric forms, a homo-oligomer in the cytosol and a hetero-oligomer on peroxisome membranes, possibly playing distinct functions in peroxisome biogenesis Homo sapiens 5737
-
peroxisome membrane, Pex1p possesses two distinct oligomeric forms, a homo-oligomer in the cytosol and a hetero-oligomer on peroxisome membranes, possibly playing distinct functions in peroxisome biogenesis Homo sapiens 5777
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peroxisome Pex6p is predominantly localized on peroxisomes Homo sapiens 5777
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Homo sapiens
-
ADP + phosphate
-
?
ATP + H2O Homo sapiens Pex1p possesses two distinct oligomeric forms, a homo-oligomer in the cytosol and a hetero-oligomer on peroxisome membranes, possibly playing distinct functions in peroxisome biogenesis ADP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
Homo sapiens
-
HEK-293 cell HsPex6p Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
Homo sapiens ADP + phosphate
-
?
ATP + H2O Pex1p possesses two distinct oligomeric forms, a homo-oligomer in the cytosol and a hetero-oligomer on peroxisome membranes, possibly playing distinct functions in peroxisome biogenesis Homo sapiens ADP + phosphate
-
?

Subunits

Subunits Comment Organism
oligomer Pex1p possesses two distinct oligomeric forms, a homo-oligomer in the cytosol and a hetero-oligomer on peroxisome membranes, possibly playing distinct functions in peroxisome biogenesis. Interaction of Pex1p with Pex6p confers a conformatinal and dissociation of the Pex1p oligomer Homo sapiens

Synonyms

Synonyms Comment Organism
HsPex1p
-
Homo sapiens
HsPex6p
-
Homo sapiens