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Literature summary for 3.6.4.6 extracted from

  • Alonso Y Adell, M.; Migliano, S.M.; Teis, D.
    ESCRT-III and Vps4 a dynamic multipurpose tool for membrane budding and scission (2016), FEBS J., 283, 3288-3302 .
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Homo sapiens
-
ADP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
Homo sapiens ADP + phosphate
-
?

Synonyms

Synonyms Comment Organism
Vps4 vacuolar protein sorting 4 Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme functions in membrane remodelling and is the only ATP consuming factor of the endosomal sorting complex required for transport (ESCRT) machinery. ATP hydrolysis is required to disassemble ESCRT-III polymers, which releases individual ESCRT-III subunits back into the cytoplasm Homo sapiens