Reference on EC 3.6.4.13 - RNA helicase and Organism(s) Homo sapiens and UniProt Accession P17844
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Rodamilans, B.; Montoya, G.
Expression, purification, crystallization and preliminary X-ray diffraction analysis of the DDX3 RNA helicase domain
Acta Crystallogr. Sect. F
63
283-286
2007
Homo sapiens (O00571), Homo sapiens
Abdelhaleem, M.
RNA helicases: regulators of differentiation
Clin. Biochem.
38
499-503
2005
Homo sapiens (O00571), Homo sapiens (O15523), Homo sapiens (Q9NQI0), Homo sapiens (Q9UHL0), Homo sapiens, Mus musculus (Q501J6), Mus musculus (Q61656), Mus musculus (Q9QY15), Rattus norvegicus (Q9QY16)
Lee, C.G.; Hurwitz, J.
A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3' to 5' direction.
J. Biol. Chem.
267
4398-4407
1992
Homo sapiens
Flores-Rozas, H.; Hurwitz, J.
Characterization of a new RNA helicase from nuclear extracts of HeLa cells which translocates in the 5' to 3' direction.
J. Biol. Chem.
268
21372-21383
1993
Homo sapiens
Gutti, R.K.; Tsai-Morris, C.H.; Dufau, M.L.
Gonadotropin-regulated testicular helicase (DDX25), an essential regulator of spermatogenesis, prevents testicular germ cell apoptosis
J. Biol. Chem.
283
17055-17064
2008
Homo sapiens (Q9UHL0)
Imamura, O.; Saiki, K.; Tani, T.; Ohshima, Y.; Sugawara, M.; Furuichi. Y.
Cloning and characterization of a human DEAH-box RNA helicase, a functional homolog of fission yeast Cdc28/Prp8
Nucleic Acids Res.
26
2063-2068
1998
Homo sapiens (O60231), Homo sapiens
Vlineva, T.; Yang, J.; Silvennoinen, O.
Characterization of RNA helicase A as component of STAT6-dependent enhanceosome
Nucleic Acids Res.
34
3938-3946
2006
Homo sapiens
Noble, C.G.; Song, H.
MLN51 stimulates the RNA-helicase activity of eIF4AIII
PLoS One
21
e303
2007
Homo sapiens (P38919)
Tang, W.; You, W.; Shi, F.; Qi, T.; Wang, L.; Djouder, Z.; Liu, W.; Zeng, X.
RNA helicase A acts as a bridging factor linking nuclear beta-actin with RNA polymerase II
Biochem. J.
420
421-428
2009
Homo sapiens
Hahn, D.; Beggs, J.D.
Brr2p RNA helicase with a split personality: insights into structure and function
Biochem. Soc. Trans.
38
1105-1109
2010
Homo sapiens
Collins, R.; Karlberg, T.; Lehtioe, L.; Schuetz, P.; van den Berg, S.; Dahlgren, L.G.; Hammarstroem, M.; Weigelt, J.; Schueler, H.
The DEXD/H-box RNA helicase DDX19 is regulated by an alpha-helical switch
J. Biol. Chem.
284
10296-10300
2009
Homo sapiens (Q9UMR2), Homo sapiens
Schuetz, P.; Wahlberg, E.; Karlberg, T.; Hammarstroem, M.; Collins, R.; Flores, A.; Schueler, H.
Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein
J. Mol. Biol.
400
768-782
2010
Homo sapiens (Q08211), Homo sapiens
Minshall, N.; Kress, M.; Weil, D.; Standart, N.
Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly
Mol. Biol. Cell
20
2464-2472
2009
Homo sapiens (P26196), Homo sapiens
Carter, C.L.; Lin, C.; Liu, C.Y.; Yang, L.; Liu, Z.R.
Phosphorylated p68 RNA helicase activates Snail1 transcription by promoting HDAC1 dissociation from the Snail1 promoter
Oncogene
29
5427-5436
2010
Homo sapiens
Ranji, A.; Shkriabai, N.; Kvaratskhelia, M.; Musier-Forsyth, K.; Boris-Lawrie, K.
Features of double-stranded RNA-binding domains of RNA helicase A are necessary for selective recognition and translation of complex mRNAs
J. Biol. Chem.
286
5328-5337
2011
Homo sapiens
Choi, Y.J.; Lee, S.G.
The DEAD-box RNA helicase DDX3 interacts with DDX5, co-localizes with it in the cytoplasm during the G2/M phase of the cycle, and affects its shuttling during mRNP export
J. Cell. Biochem.
113
985-996
2012
Homo sapiens, Homo sapiens (P17844)
Kar, A.; Fushimi, K.; Zhou, X.; Ray, P.; Shi, C.; Chen, X.; Liu, Z.; Chen, S.; Wu, J.Y.
RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5 splice site
Mol. Cell. Biol.
31
1812-1821
2011
Homo sapiens (P17844)
Booy, E.P.; Meier, M.; Okun, N.; Novakowski, S.K.; Xiong, S.; Stetefeld, J.; McKenna, S.A.
The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary
Nucleic Acids Res.
40
4110-4124
2012
Homo sapiens
Manojlovic, Z.; Stefanovic, B.
A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs
RNA
18
321-334
2012
Homo sapiens
Xing, L.; Niu, M.; Zhao, X.; Kleiman, L.
Different activities of the conserved lysine residues in the double-stranded RNA binding domains of RNA helicase A in vitro and in the cell
Biochim. Biophys. Acta
1840
2234-2243
2014
Homo sapiens (Q08211)
Chen, G.; Liu, C.H.; Zhou, L.; Krug, R.M.
Cellular DDX21 RNA helicase inhibits influenza A virus replication but is counteracted by the viral NS1 protein
Cell Host Microbe
15
484-493
2014
Homo sapiens (Q9NR30)
Hug, N.; Caceres, J.F.
The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex
Cell Rep.
8
1845-1856
2014
Homo sapiens (Q14147), Homo sapiens
Leitao, A.L.; Costa, M.C.; Enguita, F.J.
Unzippers, resolvers and sensors: a structural and functional biochemistry tale of RNA helicases
Int. J. Mol. Sci.
16
2269-2293
2015
Saccharomyces cerevisiae, Saccharomyces cerevisiae (P21372), Saccharomyces cerevisiae (P47047), Dengue virus, Hepacivirus C, Neurospora crassa, Yellow fever virus, Homo sapiens (O95786), Homo sapiens (Q9UMR2), Murray Valley encephalitis virus (P05769), Kunjin virus (P14335), Japanese encephalitis virus (P27395)
Guo, M.; Hundseth, K.; Ding, H.; Vidhyasagar, V.; Inoue, A.; Nguyen, C.H.; Zain, R.; Lee, J.S.; Wu, Y.
A distinct triplex DNA unwinding activity of ChlR1 helicase
J. Biol. Chem.
290
5174-5189
2015
Homo sapiens (Q96FC9), Homo sapiens
Fiorini, F.; Bagchi, D.; Le Hir, H.; Croquette, V.
Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activities
Nat. Commun.
6
7581
2015
Homo sapiens (Q92900), Homo sapiens
Erkizan, H.V.; Schneider, J.A.; Sajwan, K.; Graham, G.T.; Griffin, B.; Chasovskikh, S.; Youbi, S.E.; Kallarakal, A.; Chruszcz, M.; Padmanabhan, R.; Casey, J.L.; Ueren, A.; Toretsky, J.A.
RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1
Nucleic Acids Res.
43
1069-1080
2015
Homo sapiens (Q08211)
Felisberto-Rodrigues, C.; Thomas, J.C.; McAndrew, C.; Le Bihan, Y.V.; Burke, R.; Workman, P.; van Montfort, R.L.M.
Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release
Biochem. J.
476
2521-2543
2019
Homo sapiens (Q14562), Homo sapiens
Xie, Q.; Liu, J.; Shan, Y.; Wang, S.; Liu, F.
Substrate determinants for unwinding activity of the DExH/D-Box protein RNA helicase A
Biochemistry
57
6662-6668
2018
Homo sapiens (Q08211)
Giraud, G.; Terrone, S.; Bourgeois, C.F.
Functions of DEAD box RNA helicases DDX5 and DDX17 in chromatin organization and transcriptional regulation
BMB Rep.
51
613-622
2018
Drosophila melanogaster, Drosophila melanogaster (P19109), Homo sapiens (P17844), Homo sapiens (Q92841), Mus musculus (Q501J6), Mus musculus (Q61656)
Absmeier, E.; Santos, K.F.; Wahl, M.C.
Functions and regulation of the Brr2 RNA helicase during splicing
Cell Cycle
15
3362-3377
2016
Homo sapiens (O75643), Homo sapiens, Saccharomyces cerevisiae (P32639), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 (P32639)
Absmeier, E.; Becke, C.; Wollenhaupt, J.; Santos, K.F.; Wahl, M.C.
Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2
Cell Cycle
16
100-112
2017
Thermochaetoides thermophila (G0S0B9), Homo sapiens (O75643), Thermochaetoides thermophila IMI 039719 (G0S0B9), Thermochaetoides thermophila DSM 1495 (G0S0B9), Thermochaetoides thermophila CBS 144.50 (G0S0B9)
Hashemi, V.; Masjedi, A.; Hazhir-Karzar, B.; Tanomand, A.; Shotorbani, S.S.; Hojjat-Farsangi, M.; Ghalamfarsa, G.; Azizi, G.; Anvari, E.; Baradaran, B.; Jadidi-Niaragh, F.
The role of DEAD-box RNA helicase p68 (DDX5) in the development and treatment of breast cancer
J. Cell. Physiol.
234
5478-5487
2019
Homo sapiens (P17844), Homo sapiens
Iwatani-Yoshihara, M.; Ito, M.; Klein, M.G.; Yamamoto, T.; Yonemori, K.; Tanaka, T.; Miwa, M.; Morishita, D.; Endo, S.; Tjhen, R.; Qin, L.; Nakanishi, A.; Maezaki, H.; Kawamoto, T.
Discovery of allosteric inhibitors targeting the spliceosomal RNA helicase Brr2
J. Med. Chem.
60
5759-5771
2017
Homo sapiens (O75643)
De, I.; Bessonov, S.; Hofele, R.; dos Santos, K.; Will, C.L.; Urlaub, H.; Luehrmann, R.; Pena, V.
The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes
Nat. Struct. Mol. Biol.
22
138-144
2015
Homo sapiens (O60306), Homo sapiens
Gowravaram, M.; Bonneau, F.; Kanaan, J.; Maciej, V.D.; Fiorini, F.; Raj, S.; Croquette, V.; Le Hir, H.; Chakrabarti, S.
A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner
Nucleic Acids Res.
46
2648-2659
2018
Homo sapiens (Q92900)
