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Information on EC 3.5.4.35 - tRNA(cytosine8) deaminase

for references in articles please use BRENDA:EC3.5.4.35

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IUBMB Comments

The enzyme from Methanopyrus kandleri specifically catalyses the deamimation of cytosine at position 8 of tRNA in 30 different tRNAs. This cytosine-to-uracil editing guarantees the proper folding and functionality of the tRNAs.

The expected taxonomic range for this enzyme is: Methanopyrus kandleri
Reaction Schemes
cytosine8 in tRNA
+
=
uracil8 in tRNA
+

Synonyms
cdat8, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
cytosine8 in tRNA + H2O = uracil8 in tRNA + NH3
show the reaction diagram
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