Reference on EC 3.4.22.56 - caspase-3 and Organism(s) Mus musculus and UniProt Accession P70677
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van de Craen, M.; Berx, G.; van den Brande, I.; Fiers, W.; Declercq, W.; Vandenabeele, P.
Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis
FEBS Lett.
458
167-170
1999
Mus musculus
van de Craen, M.; Vandenabeele, P.; Declercq, W.; van den Brande, I.; van Loo, G.; Molemans, F.; Schotte, P.; van Criekinge, W.; Beyaert, R.; Fiers, W.
Characterization of seven murine caspase family members
FEBS Lett.
403
61-69
1997
Mus musculus (P70677), Mus musculus, Mus musculus C3H/An (P70677)
Mukasa, T.; Urase, K.; Momoi, M.Y.; Kimura, I.; Momoi, T.
Specific expression of CPP32 in sensory neurons of mouse embryos and activation of CPP32 in the apoptosis induced by a withdrawal of NGF
Biochem. Biophys. Res. Commun.
231
770-774
1997
Mus musculus (P70677), Mus musculus
Djerbi, M.; Darreh-Shori, T.; Zhivotovsky, B.; Grandien, A.
Characterization of the human FLICE-inhibitory protein locus and comparison of the anti-apoptotic activity of four different FLIP isoforms
Scand. J. Immunol.
54
180-189
2001
Mus musculus
Han, B.H.; Xu, D.; Choi, J.; Han, Y.; Xanthoudakis, S.; Roy, S.; Tam, J.; Vaillancourt, J.; Colucci, J.; Siman, R.; Giroux, A.; Robertson, G.S.; Zamboni, R.; Nicholson, D.W.; Holtzman, D.M.
Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury
J. Biol. Chem.
277
30128-30136
2002
Homo sapiens, Mus musculus
Deveraux, Q.L.; Roy, N.; Stennicke, H.R.; Van Arsdale, T.; Zhou, Q.; Srinivasula, S.M.; Alnemri, E.S.; Salvesen, G.S.; Reed, J.C.
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
EMBO J.
17
2215-2223
1998
Homo sapiens, Mus musculus
Zhang, Y.; Bhavnani, B.R.
Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens
BMC Neurosci.
7
49
2006
Mus musculus, Rattus norvegicus
Burkhardt, B.R.; Greene, S.R.; White, P.; Wong, R.K.; Brestelli, J.E.; Yang, J.; Robert, C.E.; Brusko, T.M.; Wasserfall, C.H.; Wu, J.; Atkinson, M.A.; Gao, Z.; Kaestner, K.H.; Wolf, B.A.
PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21)
Gene
369
134-141
2006
Mus musculus, Mus musculus C57/BL6
Kiang, J.G.; Bowman, P.D.; Lu, X.; Li, Y.; Wu, B.W.; Loh, H.H.; Tsen, K.T.; Tsokos, G.C.
Geldanamycin inhibits hemorrhage-induced increases in caspase-3 activity: role of inducible nitric oxide synthase
J. Appl. Physiol.
103
1045-1055
2007
Mus musculus
Samuel, M.A.; Morrey, J.D.; Diamond, M.S.
Caspase 3-dependent cell death of neurons contributes to the pathogenesis of West Nile virus encephalitis
J. Virol.
81
2614-2623
2007
Mus musculus
Andersen, A.D.; Poulsen, K.A.; Lambert, I.H.; Pedersen, S.F.
HL-1 mouse cardiomyocyte injury and death after simulated ischemia and reperfusion: roles of pH, Ca2+-independent phospholipase A2, and Na+/H+ exchange
Am. J. Physiol. Cell Physiol.
296
C1277-C1242
2009
Mus musculus, Mus musculus HL-1
Nomura, M.; Takahashi, T.; Uesugi, A.; Tanaka, R.; Kobayashi, S.
Inotodiol, a lanostane triterpenoid, from Inonotus obliquus inhibits cell proliferation through caspase-3-dependent apoptosis
Anticancer Res.
28
2691-2696
2008
Mus musculus
Johnke, R.M.; Smith, E.S.; Cariveau, M.J.; Evans, M.J.; Kilburn, J.M.; Bakken, N.T.; Nangami, G.N.
Radioprotection of murine gastrointestinal epithelium by interleukin-1alpha involves down-regulation of the apoptotic response
Anticancer Res.
28
3601-3607
2009
Mus musculus, Mus musculus C57BL/6
Yi, J.Y.; Hirabayashi, Y.; Choi, Y.K.; Kodama, Y.; Kanno, J.; Han, J.H.; Inoue, T.; Yoon, B.I.
Benzene activates caspase-4 and -12 at the transcription level, without an association with apoptosis, in mouse bone marrow cells lacking the p53 gene
Arch. Toxicol.
83
795-803
2009
Mus musculus
Calafat, M.; Larocca, L.; Roca, V.; Hauk, V.; Pregi, N.; Nesse, A.; Perez Leiros, C.
Vasoactive intestinal peptide inhibits tumor necrosis factor-alpha-induced apoptotic events in acinar cells from non-obese diabetic mice submandibular glands
Arthritis Res. Ther.
11
R53
2009
Mus musculus
Jen, C.Y.; Lin, C.Y.; Leu, S.F.; Huang, B.M.
Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis through caspase-9 pathway
Evid. Based. Complement Alternat. Med.
2009
1-10
2009
Mus musculus
French, C.J.; Spees, J.L.; Zaman, A.K.; Taatjes, D.J.; Sobel, B.E.
The magnitude and temporal dependence of apoptosis early after myocardial ischemia with or without reperfusion
FASEB J.
23
1177-1185
2009
Mus musculus, Mus musculus C57BL6
Bogazzi, F.; Ultimieri, F.; Raggi, F.; Russo, D.; Lombardi, M.; Cosci, C.; Brogioni, S.; Gasperi, M.; Bartalena, L.; Martino, E.
Reduced colonic apoptosis in mice overexpressing bovine growth hormone occurs through changes in several kinase pathways
Growth Horm. IGF Res.
19
432-441
2009
Mus musculus
Jin, D.; Ojcius, D.M.; Sun, D.; Dong, H.; Luo, Y.; Mao, Y.; Yan, J.
Leptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways
Infect. Immun.
77
799-809
2009
Homo sapiens, Mus musculus
Harikumar, K.B.; Kuttan, G.; Kuttan, R.
Phyllanthus amarus inhibits cell growth and induces apoptosis in Dalton's lymphoma ascites cells through activation of caspase 3 and down regulation of bcl-2
Integr. Cancer Ther.
8
190-194
2009
Mus musculus, Mus musculus BALB/c
Barry, G.M.; Breakwell, L.; Fragkoudis, R.; Attarzadeh-Yazdi, G.; Rodriguez-Andres, J.; Kohl, A.; Fazakerley, J.K.
PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type-I interferon response
J. Gen. Virol.
90
1382-1391
2009
Mus musculus
Caballero, B.; Vega-Naredo, I.; Sierra, V.; Huidobro-Fernandez, C.; Soria-Valles, C.; De Gonzalo-Calvo, D.; Tolivia, D.; Pallas, M.; Camins, A.; Rodriguez-Colunga, M.J.; Coto-Montes, A.
Melatonin alters cell death processes in response to age-related oxidative stress in the brain of senescence-accelerated mice
J. Pineal Res.
46
106-114
2009
Mus musculus
Bae, K.H.; Moon, C.W.; Lee, Y.; Park, T.G.
Intracellular delivery of heparin complexed with chitosan-g-poly(ethylene glycol) for inducing apoptosis
Pharm. Res.
26
93-100
2009
Mus musculus
Bhutia, S.K.; Mallick, S.K.; Maiti, S.; Maiti, T.K.
Inhibitory effect of Abrus abrin-derived peptide fraction against Daltons lymphoma ascites model
Phytomedicine
16
377-385
2009
Mus musculus
Kim, K.W.; Moretti, L.; Lu, B.
M867, a novel selective inhibitor of caspase-3 enhances cell death and extends tumor growth delay in irradiated lung cancer models
PLoS ONE
3
e2275
2008
Homo sapiens, Mus musculus
Wang, X.H.; Zhang, L.; Mitch, W.E.; LeDoux, J.M.; Hu, J.; Du, J.
Caspase-3 cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity
J. Biol. Chem.
285
21249-21257
2010
Mus musculus
Katao, Y.; Shishido, M.; Inami, K.; Matsumoto, N.; Sawai, H.
An inhibitory role for caspase-3 at the late stage of RANKL-induced osteoclast differentiation in RAW264 cells and mouse bone marrow macrophages
Cell Biol. Int.
38
723-728
2014
Mus musculus