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Information on EC 3.1.4.45 - N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

for references in articles please use BRENDA:EC3.1.4.45
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IUBMB Comments
Acts on a variety of compounds in which N-acetyl-D-glucosamine is alpha-linked to a phosphate group, including the biosynthetic intermediates of the high mannose oligosaccharide components of some lysosomal enzymes and the products of EC 2.7.8.17 UDP-N-acetylglucosamine---lysosomal-enzyme N-acetylglucosaminephosphotransferase.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
naglu, phosphodiester alpha-glcnacase, alpha-n-acetylglucosaminyl phosphodiesterase, phosphodiester glycosidase, lysosomal alpha-n-acetylglucosaminidase, n-acetylglucosamine-1-phosphodiester alpha-n-acetylglucosaminidase, n-acetylglucosamine-1-phosphodiester n-acetylglucosaminidase, glcnac-1-phosphodiester alpha-n-acetylglucosaminidase, alpha-n-acetylglucosaminylphosphodiesterase, glcnac-1-phosphodiester-n-acetylglucosaminidase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose
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