Reference on EC 3.1.3.43 - [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase and Organism(s) Homo sapiens and UniProt Accession Q9P0J1
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ito, M.; Kobashi, H.; Naito, E.; Saijo, T.; Takeda, E.; Huq, A.H.M.M.; Kuroda, Y.
Decrease of pyruvate dehydrogenase phosphatase activity in patients with congenital lactic acidemia
Clin. Chim. Acta
209
1-7
1992
Homo sapiens
Jacobia, S.J.; Korotchkina, L.G.; Patel, M.S.
Differential effects of two mutations at arginine-234 in the alpha subunit of human pyruvate dehydrogenase
Arch. Biochem. Biophys.
395
121-128
2001
Homo sapiens
Chen, H.B.; Shen, J.; Ip, Y.T.; Xu, L.
Identification of phosphatases for Smad in the BMP/DPP pathway
Genes Dev.
20
648-653
2006
Drosophila melanogaster, Homo sapiens
Maj, M.C.; MacKay, N.; Levandovskiy, V.; Addis, J.; Baumgartner, E.R.; Baumgartner, M.R.; Robinson, B.H.; Cameron, J.M.
Pyruvate dehydrogenase phosphatase deficiency: identification of the first mutation in two brothers and restoration of activity by protein complementation
J. Clin. Endocrinol. Metab.
90
4101-4107
2005
Homo sapiens
Piccinini, M.; Mostert, M.; Alberto, G.; Ramondetti, C.; Novi, R.F.; Dalmasso, P.; Rinaudo, M.T.
Down-regulation of pyruvate dehydrogenase phosphatase in obese subjects is a defect that signals insulin resistance
Obes. Res.
13
678-686
2005
Homo sapiens
Cameron, J.M.; Maj, M.; Levandovskiy, V.; Barnett, C.P.; Blaser, S.; Mackay, N.; Raiman, J.; Feigenbaum, A.; Schulze, A.; Robinson, B.H.
Pyruvate dehydrogenase phosphatase 1 (PDP1) null mutation produces a lethal infantile phenotype
Hum. Genet.
125
319-326
2009
Homo sapiens (Q9P0J1), Homo sapiens (Q9P2J9), Homo sapiens
Kato, J.; Kato, M.
Crystallization and preliminary crystallographic studies of the catalytic subunits of human pyruvate dehydrogenase phosphatase isoforms 1 and 2
Acta Crystallogr. Sect. F
66
342-345
2010
Homo sapiens (Q9P0J1), Homo sapiens (Q9P2J9), Homo sapiens
Love, L.; LeBlanc, P.; Inglis, J.; Bradley, N.; Choptiany, J.; Heigenhauser, G.; Peters, S.
The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity
J. Appl. Physiol.
111
427-434
2011
Homo sapiens
Shan, C.; Kang, H.B.; Elf, S.; Xie, J.; Gu, T.L.; Aguiar, M.; Lonning, S.; Hitosugi, T.; Chung, T.W.; Arellano, M.; Khoury, H.J.; Shin, D.M.; Khuri, F.R.; Boggon, T.J.; Fan, J.
Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth
J. Biol. Chem.
289
21413-21422
2014
Homo sapiens
Kaplon, J.; Zheng, L.; Meissl, K.; Chaneton, B.; Selivanov, V.A.; Mackay, G.; van der Burg, S.H.; Verdegaal, E.M.; Cascante, M.; Shlomi, T.; Gottlieb, E.; Peeper, D.S.
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
Nature
498
109-112
2013
Homo sapiens
Wang, H.; Zhang, L.; Guo, X.; Bai, Y.; Li, Y.X.; Sha, J.; Peng, C.; Wang, Y.L.; Liu, M.
MiR-195 modulates oxidative stress-induced apoptosis and mitochondrial energy production in human trophoblasts via flavin adenine dinucleotide-dependent oxidoreductase domain-containing protein 1 and pyruvate dehydrogenase phosphatase regulatory subunit
J. Hypertens.
36
306-318
2018
Homo sapiens (Q8NCN5), Homo sapiens
Barberio, M.D.; Huffman, K.M.; Giri, M.; Hoffman, E.P.; Kraus, W.E.; Hubal, M.J.
Pyruvate dehydrogenase phosphatase regulatory gene expression correlates with exercise training insulin sensitivity changes
Med. Sci. Sports Exerc.
48
2387-2397
2016
Homo sapiens
Chen, J.; Guccini, I.; Mitri, D.; Brina, D.; Revandkar, A.; Sarti, M.; Pasquini, E.; Alajati, A.; Pinton, S.; Losa, M.; Civenni, G.; Catapano, C.; Sgrignani, J.; Cavalli, A.; DAntuono, R.; Asara, J.; Morandi, A.; Chiarugi, P.; Crotti, S.; Agostini, M.
Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
Nat. Genet.
50
219-228
2018
Homo sapiens
