Reference on EC 3.1.22.1 - deoxyribonuclease II and Organism(s) Homo sapiens and UniProt Accession O00115
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Baker, K.P.; Baron, W.F.; Henzel, W.J.; Spencer, S.A.
Molecular cloning and characterization of human and murine DNase II
Gene
215
281-289
1998
Homo sapiens, Mus musculus, Sus scrofa
Krieser, R.J.; Eastman, A.
The cloning and expression of human deoxyribonuclease II. A possible role in apoptosis
J. Biol. Chem.
273
30909-30914
1998
Homo sapiens (O00115), Homo sapiens
Takeshita, H.; Yasuda, T.; Iida, R.; Nakajima, T.; Hosomi, O.; Nakashima, Y.; Mori, S.; Nomoto, H.; Kishi, K.
Identification of the three non-identical subunits cnstituting human deoxyribonuclease II
FEBS Lett.
440
239-242
1998
Homo sapiens
Yasuda, T.; Nadano, D.; Awazu, S.; Kishi, K.
Human urine deoxyribonuclease II (DNase II) isoenzymes: a novel immunoaffinity purification, biochemical multiplicity, genetic heterogeneity and broad distribution among tissues and body fluids
Biochim. Biophys. Acta
1119
185-193
1992
Homo sapiens
Harosh, I.; Binninger, D.M.; Harris, P.V.; Mezzina, M.; Boyd, J.B.
Mechanism of action of deoxyribonuclease II from human lymphoblasts
Eur. J. Biochem.
202
479-484
1991
Homo sapiens
Murai, K.; Yamanaka, M.; Akagi, K.; Anai, M.
Purification and properties of deoxyribonuclease II from human urine
J. Biochem.
87
1097-1103
1980
Homo sapiens
Slor, H.
Purification of 14C-labelled deoxyribonuclease II from HeLa S3 lysosomes and its use as a marker for the study of nuclear deoxyribonuclease II
Biochem. J.
136
83-87
1973
Homo sapiens
Schroeder, W.A.; Shelton, R.J.; Shelton, J.B.; Robberson, B.; Apell, G.
DNase II inhibitor in tissues and urine - pH and salt artifacts
Arch. Biochem. Biophys.
131
652-658
1969
Homo sapiens
MacLea, K.S.; Krieser, R.J.; Eastman, A.
Revised structure of the active form of human deoxyribonuclease IIalpha
Biochem. Biophys. Res. Commun.
292
415-421
2002
Homo sapiens (Q8WZ79), Homo sapiens
MacLea, K.S.; Krieser, R.J.; Eastman, A.
Structural requirements of human DNase II alpha for formation of the active enzyme: the role of the signal peptide, N-glycosylation, and disulphide bridging
Biochem. J.
371
867-876
2003
Homo sapiens
Chou, S.F.; Chen, H.L.; Lu, S.C.
Sp1 and Sp3 are involved in up-regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells
Eur. J. Biochem.
270
1855-1862
2003
Homo sapiens
Krieser, R.J.; MacLea, K.S.; Park, J.P.; Eastman, A.
The cloning, genomic structure, localization, and expression of human deoxyribonuclease IIbeta
Gene
269
205-216
2001
Homo sapiens (Q8WZ79), Homo sapiens, Mus musculus
MacLea, K.S.; Krieser, R.J.; Eastman, A.
A family history of deoxyribonuclease II: surprises from Trichinella spiralis and Burkholderia pseudomallei
Gene
305
1-12
2003
Bos taurus (P56541), Caenorhabditis elegans (P34387), Caenorhabditis elegans (P34508), Caenorhabditis elegans (Q17778), Caenorhabditis elegans, Caenorhabditis elegans F09G8.2 (P34387), Caenorhabditis elegans K04H4.6 (P34508), Caenorhabditis elegans NUC-1 (Q17778), Drosophila melanogaster (Q7JYM9), Homo sapiens (O00115), Homo sapiens (Q8WZ79), Homo sapiens, Mus musculus (P56542), Mus musculus (Q9QY48), Rattus norvegicus (Q9QZK8), Rattus norvegicus (Q9QZK9), Sus scrofa (O62855)
Evans, C.J.; Aguilera, R.J.
DNase II: genes, enzymes and function
Gene
322
1-15
2003
Caenorhabditis elegans, Caenorhabditis elegans NUC-1, Drosophila melanogaster, Homo sapiens, Mus musculus
Cymerman, I.A.; Meiss, G.; Bujnicki, J.M.
DNase II is a member of the phospholipase D superfamily
Bioinformatics
21
3959-3962
2005
Homo sapiens
Shin, H.D.; Park, B.L.; Cheong, H.S.; Lee, H.S.; Jun, J.B.; Bae, S.C.
DNase II polymorphisms associated with risk of renal disorder among systemic lupus erythematosus patients
J. Hum. Genet.
50
107-111
2005
Homo sapiens
Brossas, J.Y.; Tanguy, R.; Brignole-Baudouin, F.; Courtois, Y.; Torriglia, A.; Treton, J.
L-DNase II associated with active process during ethanol induced cell death in ARPE-19
Mol. Vis.
10
65-73
2004
Homo sapiens
Cherepanova, A.; Tamkovich, S.; Pyshnyi, D.; Kharkova, M.; Vlassov, V.; Laktionov, P.
Immunochemical assay for deoxyribonuclease activity in body fluids
J. Immunol. Methods
325
96-103
2007
Homo sapiens
Schaefer, P.; Cymerman, I.A.; Bujnicki, J.M.; Meiss, G.
Human lysosomal DNase IIalpha contains two requisite PLD-signature (HxK) motifs: evidence for a pseudodimeric structure of the active enzyme species
Protein Sci.
16
82-91
2007
Homo sapiens
Torriglia, A.; Lepretre, C.; Padron-Barthe, L.; Chahory, S.; Martin, E.
Molecular mechanism of L-DNase II activation and function as a molecular switch in apoptosis
Biochem. Pharmacol.
76
1490-1502
2008
Gallus gallus, Cricetulus griseus, Homo sapiens, Mus musculus, Rattus norvegicus
Lepretre, C.; Fleurier, Y.; Martin, E.; Torriglia, A.
Nuclear export of LEI/L-DNase II by Crm1 is essential for cell survival
Biochim. Biophys. Acta
1783
1068-1075
2008
Cricetulus griseus, Homo sapiens, Sus scrofa
Liu, M.F.; Wu, X.P.; Wang, X.L.; Yu, Y.L.; Wang, W.F.; Chen, Q.J.; Boireau, P.; Liu, M.Y.
The functions of Deoxyribonuclease II in immunity and development
DNA Cell Biol.
27
223-228
2008
Acanthaster planci, Drosophila sp. (in: flies), Haemonchus contortus, Homo sapiens, Mus musculus, Sus scrofa, Trichinella spiralis
Ueki, M.; Takeshita, H.; Fujihara, J.; Kimura-Kataoka, K.; Iida, R.; Yuasa, I.; Nakajima, T.; Kominato, Y.; Yasuda, T.
Genetic and expression analysis of all 7 non-synonymous single nucleotide polymorphisms in the human deoxyribonuclease II gene, with potential relevance to autoimmunity
Clin. Chim. Acta
411
92-98
2010
Homo sapiens (O00115), Homo sapiens
Fischer, H.; Scherz, J.; Szabo, S.; Mildner, M.; Benarafa, C.; Torriglia, A.; Tschachler, E.; Eckhart, L.
DNase 2 is the main DNA-degrading enzyme of the stratum corneum
PLoS ONE
6
e17581
2011
Homo sapiens, Mus musculus