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Information on EC 2.7.1.176 - UDP-N-acetylglucosamine kinase

for references in articles please use BRENDA:EC2.7.1.176
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IUBMB Comments
Toxic component of a toxin-antitoxin (TA) module. The phosphorylation of UDP-N-acetyl-D-glucosamine results in the inhibition of EC 2.5.1.7, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, the first committed step in cell wall synthesis, which is then blocked. The activity of this enzyme is inhibited when the enzyme binds to the cognate epsilon antitoxin.
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The enzyme appears in viruses and cellular organisms
Synonyms
zeta toxin, toxin pezt, toxin zeta, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + UDP-N-acetyl-alpha-D-glucosamine = ADP + UDP-N-acetyl-alpha-D-glucosamine 3'-phosphate
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