Cloned (Comment) | Organism |
---|---|
the gene is encoded in plasmid pSM19035. The omega-epsilon-zeta operon of this plasmid constitutes a proteic plasmid addiction system in which the epsilon and zeta genes encode an antitoxin and toxin, respectively, while omega plays an autoregulatory function | Streptococcus pyogenes |
Protein Variants | Comment | Organism |
---|---|---|
A111C | deletion of one A in the AAAAAAA tract, which begins at the 78-nt position, results in a frameshift and the stop codon formation after 51 codons, additional mutations are insertion of G after A32 and A111C substitution in one case and A248G substitution in the second one | Streptococcus pyogenes |
A248G | deletion of one A in the AAAAAAA tract, which begins at the 78-nt position, results in a frameshift and the stop codon formation after 51 codons, additional mutations are insertion of G after A32 and A111C substitution in one case and A248G substitution in the second one | Streptococcus pyogenes |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pyogenes | Q54944 | the gene is encoded in plasmid pSM19035 | - |
Synonyms | Comment | Organism |
---|---|---|
toxin zeta | - |
Streptococcus pyogenes |
General Information | Comment | Organism |
---|---|---|
physiological function | toxin zeta is bactericidal for the gram-positive Bacillus subtilis and bacteriostatic for the gram-negative Escherichia coli, counteracted by proper expression of epsilon. Functioning of the omega-epsilon-zeta operon as a stabilizing cassette in Bacillus subtilis and Escherichia coli cells, mechanism, overview | Streptococcus pyogenes |