Ligand UDP-N-acetyl-alpha-D-glucosamine

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Basic Ligand Information

Molecular Structure
Picture of UDP-N-acetyl-alpha-D-glucosamine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C17H27N3O17P2
UDP-N-acetyl-alpha-D-glucosamine
LFTYTUAZOPRMMI-CFRASDGPSA-N
Synonyms:
N-acetylglucosamine-UDP, UDP-acetylglucosamine, UDP-alpha-D-N-acetylglucosamine, UDP-alpha-N-acetyl-2-amino-2-deoxy-D-glucose, UDP-alpha-N-acetyl-D-glucosamine, UDP-alpha-N-acetylglucosamine, UDP-GlcNAc, UDP-N-acetyl-D-glucosamin, UDP-N-acetyl-D-glucosamine, UDP-N-acetyl-glucosamine, UDP-N-acetyl glucosamine, UDP-N-acetylglucosamine, UDP-N-acetylgucosamine, UDP-N-alpha-D-acetylglucosamine, UDPacetylglucosamine, UDPGlcNAc, uridine-diphospho-N-acetylglucosamine, uridine 5'-diphospho-N-acetyl-D-glucosamine, uridine 5'-diphospho-N-acetylglucosamine, Uridine diphosphate N-acetylglucosamine, uridine diphospho-N-acetylglucosamine
Pathway Source
Pathways
MetaCyc
2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol biosynthesis, anhydromuropeptides recycling I, bacillithiol biosynthesis, beta-D-galactosaminyl-(1rarr3)-N-acetyl-alpha-D-galactosamine biosynthesis, chitin biosynthesis more


Show all pahtways known for Show all BRENDA pathways known for UDP-N-acetyl-alpha-D-glucosamine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (198 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-N-acetyl-alpha-D-glucosamine + NAD+ = UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+
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UDP-N-acetyl-D-glucosamine + 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose = UDP + 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose
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UDP-N-acetyl-alpha-D-glucosamine + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol = UDP + N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
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UDP-N-acetyl-D-glucosamine + 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R = UDP + 3-(2,4-bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R
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UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R
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UDP-N-acetyl-D-glucosamine + lactosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
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[Notch]-fucose + UDP-alpha-D-N-acetylglucosamine = [Notch]-(3-O-beta-D-N-acetylglucosaminyl)fucose + UDP
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UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1-3)-beta-D-galactosyl-(1-3)-beta-D-galactosyl-(1-4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-beta-D-galactosyl-(1-3)-beta-D-galactosyl-(1-4)-beta-D-xylosyl-proteoglycan
show the reaction diagram
UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan = UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan
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UDP-N-acetyl-D-glucosamine + 1D-myo-inositol 3-phosphate = 1-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + UDP
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UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] = UDP + 3-O-[N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein]
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UDP-N-acetyl-D-glucosamine + polyribitol phosphate = N-acetyl-beta-D-glucosaminyl-polyribitol phosphate
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17alpha-estradiol-3-glucuronoside + UDP-N-acetylglucosamine = UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
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UDP-N-acetyl-D-glucosamine + poly(ribitol phosphate) = UDP + N-acetyl-D-glucosaminyl-poly(ribitol phosphate)
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UDP-N-acetyl-D-glucosamine + ursodeoxycholate = UDP + 7beta-(N-acetyl-D-glucosaminyl)-ursodeoxycholate
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UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
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UDP-galactose + UDP-N-acetyl-D-glucosamine = UMP + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine
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UDP-N-acetyl-alpha-D-glucosamine + trans,octacis-decaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
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UDP-N-acetyl-alpha-D-glucosamine + H2O = N-acetyl-D-mannosamine + UDP
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UDP-N-acetyl-alpha-D-glucosamine + H2O = uridine-5'-diphosphate + N-acetyl-alpha-D-glucosamine
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UDP-N-acetyl-alpha-D-glucosamine + H2O = UMP + N-acetyl-alpha-D-glucosaminyl-1-phosphate
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UDP-N-acetyl-alpha-D-glucosamine = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + H2O
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In Vivo Product in Enzyme-catalyzed Reactions (79 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-N-acetylgalactosamine = UDP-N-acetylglucosamine
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Substrate in Enzyme-catalyzed Reactions (972 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-N-acetylglucosamine + NAD+ + H2O = ? + NADH
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UDP-N-acetyl-alpha-D-glucosamine + NAD+ = UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+
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UDP-N-acetyl-alpha-D-glucosamine + D-fructose = UDP + 2-acetamido-2-deoxy-D-glucopyranosyl-beta-D-fructofuranoside
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UDP-N-acetyl glucosamine + 4-methylumbelliferyl-beta-D-xylopyranoside = ?
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UDP-GlcNAc + Galbeta(1-3)Gal = GlcNAcbeta(1-3)Galbeta(1-3)Gal + UDP
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UDP-N-acetyl-D-glucosamine + 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose = UDP + 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose
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UDP-N-acetyl-alpha-D-glucosamine + chondroitin sulfate oligosaccharide = UDP + N-acetyl-beta-D-glucosaminyl chondroitin sulfate oligosaccharide
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UDP-N-acetyl-D-glucosamine + alpha-D-glucuronosyl-(1-4)-N-acetylglucoside = UDP + alpha-N-acetyl-D-glucosaminyl-alpha-D-glucuronosyl-(1-4)-N-acetylglucoside
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UDP-N-acetyl-alpha-D-glucosamine + 2-deoxystreptamine = UDP + 2'-N-acetylparomamine
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UDP-N-acetyl-alpha-D-glucosamine + 2-deoxystreptamine = UDP + 2'-N-acetylparomamine
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UDP-N-acetyl-alpha-D-glucosamine + ribostamycin = UDP + 2'''-acetyl-6'''-hydroxyneomycin C
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