Reference on EC 2.7.1.150 - 1-phosphatidylinositol-3-phosphate 5-kinase
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Cooke, F.T.; Dove, S.K.; McEwen, R.K.; Painter, G.; Holmes, A.B.; Hall, M.N.; Michell, R.H.; Parker, P.J.
The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae
Curr. Biol.
8
1219-1222
1998
Saccharomyces cerevisiae
Gary, J.D.; Sato, T.K.; Stefan, C.J.; Bonangelino, C.J.; Weisman, L.S.; Emr, S.D.
Regulation of fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by vac7 protein and fig4, a polyphosphoinositide phosphatase family member
Mol. Biol. Cell
13
1238-1251
2002
Saccharomyces cerevisiae
Morishita, M.; Morimoto, F.; Kitamura, K.; Koga, T.; Fukui, Y.; Maekawa, H.; Yamashita, I.; Shimoda, C.
Phosphatidylinositol 3-phosphate 5-kinase is required for the cellular response to nutritional starvation and mating pheromone signals in Schizosaccharomyces pombe
Genes Cells
7
199-215
2002
Schizosaccharomyces pombe
Cooke, F.T.
Phosphatidylinositol 3,5-bisphosphate: metabolism and function
Arch. Biochem. Biophys.
407
143-151
2002
Arabidopsis thaliana, Caenorhabditis elegans, Candida albicans, Drosophila melanogaster, Homo sapiens, Mus musculus, Oryza sativa, Schizosaccharomyces pombe, Saccharomyces cerevisiae (P34756)
Dove, S.K.; McEwen, R.K.; Mayes, A.; Hughes, D.C.; Beggs, J.D.; Michell, R.H.
Vac14 controls PtdIns(3,5)P2 synthesis and Fab1-dependent protein trafficking to the multivesicular body
Curr. Biol.
12
885-893
2002
Saccharomyces cerevisiae, Schizosaccharomyces pombe
Shojaiefard, M.; Strutz-Seebohm, N.; Tavare, J.M.; Seebohm, G.; Lang, F.
Regulation of the Na(+), glucose cotransporter by PIKfyve and the serum and glucocorticoid inducible kinase SGK1
Biochem. Biophys. Res. Commun.
359
843-847
2007
Homo sapiens
Cabezas, A.; Pattni, K.; Stenmark, H.
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene
371
34-41
2006
Homo sapiens (Q9Y2I7), Homo sapiens
Duex, J.E.; Tang, F.; Weisman, L.S.
The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover
J. Cell Biol.
172
693-704
2006
Saccharomyces cerevisiae
Rutherford, A.C.; Traer, C.; Wassmer, T.; Pattni, K.; Bujny, M.V.; Carlton, J.G.; Stenmark, H.; Cullen, P.J.
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
J. Cell Sci.
119
3944-3957
2006
Homo sapiens
Phelan, J.P.; Millson, S.H.; Parker, P.J.; Piper, P.W.; Cooke, F.T.
Fab1p and AP-1 are required for trafficking of endogenously ubiquitylated cargoes to the vacuole lumen in S. cerevisiae
J. Cell Sci.
119
4225-4234
2006
Saccharomyces cerevisiae
Nicot, A.S.; Fares, H.; Payrastre, B.; Chisholm, A.D.; Labouesse, M.; Laporte, J.
The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans
Mol. Biol. Cell
17
3062-3074
2006
Caenorhabditis elegans
Rusten, T.E.; Rodahl, L.M.; Pattni, K.; Englund, C.; Samakovlis, C.; Dove, S.; Brech, A.; Stenmark, H.
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
Mol. Biol. Cell
17
3989-4001
2006
Drosophila sp. (in: flies)
Alesutan, I.S.; Ureche, O.N.; Laufer, J.; Klaus, F.; Zuern, A.; Lindner, R.; Strutz-Seebohm, N.; Tavare, J.M.; Boehmer, C.; Palmada, M.; Lang, U.E.; Seebohm, G.; Lang, F.
Regulation of the glutamate transporter EAAT4 by PIKfyve
Cell. Physiol. Biochem.
25
187-194
2010
Mus musculus (Q9Z1T6)
Bridges, D.; Ma, J.T.; Park, S.; Inoki, K.; Weisman, L.S.; Saltiel, A.R.
Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1
Mol. Biol. Cell
23
2955-2962
2012
Mus musculus
Liu, Y.; Lai, Y.C.; Hill, E.V.; Tyteca, D.; Carpentier, S.; Ingvaldsen, A.; Vertommen, D.; Lantier, L.; Foretz, M.; Dequiedt, F.; Courtoy, P.J.; Erneux, C.; Viollet, B.; Shepherd, P.R.; Tavare, J.M.; Jensen, J.; Rider, M.H.
Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle
Biochem. J.
455
195-206
2013
Didelphis sp., Rattus norvegicus (D3ZYT8)
Venkatareddy, M.; Verma, R.; Kalinowski, A.; Patel, S.R.; Shisheva, A.; Garg, P.
Distinct requirements for vacuolar protein sorting 34 downstream effector phosphatidylinositol 3-phosphate 5-kinase in podocytes versus proximal tubular cells
J. Am. Soc. Nephrol.
27
2702-2719
2016
Mus musculus (Q9Z1T6)
Hirano, T.; Munnik, T.; Sato, M.H.
Phosphatidylinositol 3-phosphate 5-kinase, FAB1/PIKfyve kinase mediates endosome maturation to establish endosome-cortical microtubule interaction in Arabidopsis
Plant Physiol.
169
1961-1974
2015
Arabidopsis thaliana (Q9LUM0)
Gan, Q.; Wang, X.; Zhang, Q.; Yin, Q.; Jian, Y.; Liu, Y.; Xuan, N.; Li, J.; Zhou, J.; Liu, K.; Jing, Y.; Wang, X.; Yang, C.
The amino acid transporter SLC-36.1 cooperates with PtdIns3P 5-kinase to control phagocytic lysosome reformation
J. Cell Biol.
218
2619-2637
2019
Caenorhabditis elegans (G5ED98), Caenorhabditis elegans
Bhakt, P.; Shivarathri, R.; Choudhary, D.K.; Borah, S.; Kaur, R.
Fluconazole-induced actin cytoskeleton remodeling requires phosphatidylinositol 3-phosphate 5-kinase in the pathogenic yeast Candida glabrata
Mol. Microbiol.
110
425-443
2018
[Candida] glabrata
Cobley, D.; Halova, L.; Schauries, M.; Kaczmarek, A.; Franz-Wachtel, M.; Du, W.; Krug, K.; Macek, B.; Petersen, J.
Ste12/Fab1 phosphatidylinositol-3-phosphate 5-kinase is required for nitrogen-regulated mitotic commitment and cell size control
PLoS ONE
12
e0172740
2017
Schizosaccharomyces pombe (O59722), Schizosaccharomyces pombe, Schizosaccharomyces pombe ATCC 24843 (O59722), Schizosaccharomyces pombe 972 (O59722)
Kang, Y.L.; Chou, Y.Y.; Rothlauf, P.W.; Liu, Z.; Soh, T.K.; Cureton, D.; Case, J.B.; Chen, R.E.; Diamond, M.S.; Whelan, S.P.J.; Kirchhausen, T.
Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2
Proc. Natl. Acad. Sci. USA
117
20803-20813
2020
Homo sapiens (Q9Y2I7)
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