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Information on EC 2.3.3.19 - 2-phosphonomethylmalate synthase

for references in articles please use BRENDA:EC2.3.3.19
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IUBMB Comments
The enzyme, isolated from several Streptomyces species, participate in the biosynthesis of certain phosphonate antibiotics. The enzyme is analogous to EC 2.3.3.1 (Si)-citrate synthase.
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The expected taxonomic range for this enzyme is: Streptomyces
Synonyms
pmm synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetyl-CoA + H2O + 3-phosphonopyruvate = (R)-2-(phosphonomethyl)malate + CoA
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