Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.3.19 extracted from

  • Hidaka, T.; Shimotohno, K.; Morishita, T.; Seto, H.
    Studies on the biosynthesis of bialaphos (SF-1293). 18. 2-phosphinomethylmalic acid synthase: A descendant of (R)-citrate synthase? (1999), J. Antibiot., 52, 925-931.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Brevibacterium lactofermentum Streptomyces hygroscopicus

Organism

Organism UniProt Comment Textmining
Streptomyces hygroscopicus Q9LCB4
-
-
Streptomyces hygroscopicus SF-1293 Q9LCB4
-
-

General Information

General Information Comment Organism
physiological function Brevibacterium lactofermentum cells expressing the enzyme convert 2-phosphinomethylmalic acid and citric acid to demethylphosphinothricin and glutamic acid, respctively. Conversion of 2-phosphinomethylmalic acid proceeds mechanistically in a manner analogous to or identical with the tricarboxylic acid cycle pathway Streptomyces hygroscopicus