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Literature summary for 2.3.3.19 extracted from

  • Shimotohno, K.; Seto, H.; Otake, N.; Imai, S.; Satoh, A.
    Studies on the biosynthesis of bialaphos (SF-1293). 7. The absolute configuration of 2-phosphinomethylmalic acid, a biosynthetic intermediate of bialaphos (1986), J. Antibiot., 39, 1356-1359.
    View publication on PubMed
Search for more literature for 2.3.3.19

Organism

Organism UniProt Comment Textmining
Streptomyces hygroscopicus Q9LCB4
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Streptomyces hygroscopicus SF-12932 Q9LCB4
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + H2O + 3-phosphonopyruvate
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 Streptomyces hygroscopicus (R)-2-(phosphonomethyl)malate + CoA
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acetyl-CoA + H2O + 3-phosphonopyruvate
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 Streptomyces hygroscopicus SF-12932 (R)-2-(phosphonomethyl)malate + CoA
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 ?
additional information the enzyme is stereospecifically similar to R-citrate synthase purified from obligate anaerobic bacteria Streptomyces hygroscopicus ?
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additional information the enzyme is stereospecifically similar to R-citrate synthase purified from obligate anaerobic bacteria Streptomyces hygroscopicus SF-12932 ?
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General Information

General Information Comment Organism
physiological function model pathway for endogenous synthesis of bialophos and demethylphosphinothricin Streptomyces hygroscopicus