Information on EC 2.3.1.14 - glutamine N-phenylacetyltransferase

for references in articles please use BRENDA:EC2.3.1.14
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The enzyme appears in viruses and cellular organisms

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EC NUMBER
COMMENTARY hide
2.3.1.14
-
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RECOMMENDED NAME
GeneOntology No.
glutamine N-phenylacetyltransferase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine
show the reaction diagram
-
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
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-
-
-
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
L-phenylalanine degradation IV (mammalian, via side chain)
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-
Tyrosine metabolism
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-
Phenylalanine metabolism
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-
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SYSTEMATIC NAME
IUBMB Comments
phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
9030-00-6
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
monkey
-
-
Manually annotated by BRENDA team
no activity in Canis sp.
dog
-
-
Manually annotated by BRENDA team
no activity in Equus sp.
horse
-
-
Manually annotated by BRENDA team
no activity in Felis sp.
cat
-
-
Manually annotated by BRENDA team
no activity in Macaca fuscata
monkey
-
-
Manually annotated by BRENDA team
no activity in Oryctolagus cuniculus
rabbit
-
-
Manually annotated by BRENDA team
no activity in Ovis aries
sheep
-
-
Manually annotated by BRENDA team
no activity in Rattus norvegicus
rat
-
-
Manually annotated by BRENDA team
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
benzoyl-CoA + glycine
CoA + benzoylglycine
show the reaction diagram
phenylacetyl-CoA + glycine
CoA + phenylacetylglycine
show the reaction diagram
phenylacetyl-CoA + L-glutamine
CoA + alpha-N-phenylacetyl-L-glutamine
show the reaction diagram
-
-
-
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
phenylacetyl-CoA + L-glutamine
CoA + alpha-N-phenylacetyl-L-glutamine
show the reaction diagram
-
-
-
?
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
specific activity in various organs
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8.8 - 10
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-
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TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
37.5
-
assay at
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
additional information
-
no activity in heart and lung
Manually annotated by BRENDA team
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30000
-
gel filtration
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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
50% loss of activity after lyophilization
-
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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-15�C, stable for several months
-
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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
partial
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LINKS TO OTHER DATABASES (specific for EC-Number 2.3.1.14)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)