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Literature summary for 2.3.1.14 extracted from

  • Moldave, K.; Meister, A.
    Synthesis of phenylacetylglutamine by human tissue (1957), J. Biol. Chem., 229, 463-476.
    View publication on PubMed

General Stability

General Stability Organism
50% loss of activity after lyophilization Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phenylacetyl-CoA + L-glutamine Homo sapiens
-
CoA + alpha-N-phenylacetyl-L-glutamine
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
no activity in Canis sp.
-
dog
-
no activity in Equus sp.
-
horse
-
no activity in Felis sp.
-
cat
-
no activity in Macaca fuscata
-
monkey
-
no activity in Oryctolagus cuniculus
-
rabbit
-
no activity in Ovis aries
-
sheep
-
no activity in Rattus norvegicus
-
rat
-

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Homo sapiens
-
liver
-
Homo sapiens
-

Storage Stability

Storage Stability Organism
-15°C, stable for several months Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzoyl-CoA + glycine
-
Homo sapiens CoA + benzoylglycine
-
?
phenylacetyl-CoA + glycine
-
Homo sapiens CoA + phenylacetylglycine
-
?
phenylacetyl-CoA + L-glutamine
-
Homo sapiens CoA + alpha-N-phenylacetyl-L-glutamine
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37.5
-
assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.8 10
-
Homo sapiens