Reference on EC 2.3.1.122 - trehalose O-mycolyltransferase and Organism(s) Mycobacterium tuberculosis and UniProt Accession P9WQN8
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Wilkinson, R.J.; DesJardin, L.E.; Islam, N.; Gibson, B.M.; Kanost, R.A.; Wilkinson, K.A.; Poelman, D.; EisenachK.D.; Toossi, Z.
An increase in expression of a tuberculosis mycolyl transferase gene (fbpB) gene occurs early after infection of human monocytes
Mol. Microbiol.
39
813-821
2001
Mycobacterium tuberculosis
Kreme, L.; Maughan, W.N.; Wilson, R.A.; Dover, L.G.; Besra, G.S.
The M. tuberculosis antigen 85 complex and mycolyltransferase activity
Lett. Appl. Microbiol.
34
233-237
2002
Mycobacterium tuberculosis
Kovac, A.; Wilson, R.A.; Besra, G.S.; Filipic, M.; Kikelj, D.; Gobec, S.
New lipophilic phthalimido- and 3-phenoxybenzyl sulfonates: inhibition of antigen 85C mycolyltransferase activity and cytotoxicity
J. Enzyme Inhib. Med. Chem.
21
391-397
2006
Mycobacterium tuberculosis (P9WQN9), Mycobacterium tuberculosis H37Rv (P9WQN9)
Warrier, T.; Tropis, M.; Werngren, J.; Diehl, A.; Gengenbacher, M.; Schlegel, B.; Schade, M.; Oschkinat, H.; Daffe, M.; Hoffner, S.; Eddine, A.N.; Kaufmann, S.H.
Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis
Antimicrob. Agents Chemother.
56
1735-1743
2012
Mycobacterium tuberculosis (P9WQN9), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQN9)
Gahoi, S.; Mandal, R.S.; Ivanisenko, N.; Shrivastava, P.; Jain, S.; Singh, A.K.; Raghunandanan, M.V.; Kanchan, S.; Taneja, B.; Mandal, C.; Ivanisenko, V.A.; Kumar, A.; Kumar, R.; Open Source Drug Discovery Consortium; Ramachandran, S.
Computational screening for new inhibitors of M. tuberculosis mycolyltransferases antigen 85 group of proteins as potential drug targets
J. Biomol. Struct. Dyn.
1
30-43
2012
Mycobacterium tuberculosis
Backus, K.M.; Boshoff, H.I.; Barry, C.S.; Boutureira, O.; Patel, M.K.; DHooge, F.; Lee, S.S.; Via, L.E.; Tahlan, K.; Barry, C.E.; Davis, B.G.
Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis
Nat. Chem. Biol.
7
228-235
2011
Mycobacterium tuberculosis
Goins, C.M.; Dajnowicz, S.; Smith, M.D.; Parks, J.M.; Ronning, D.R.
Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into antigen 85 catalysis
J. Biol. Chem.
293
3651-3662
2018
Mycobacterium tuberculosis (P9WQN8), Mycobacterium tuberculosis CDC 1551 (P9WQN8)
Pant, R.; Joshi, A.; Maiti, P.; Nand, M.; Pande, V.; Chandra, S.
Identification of potential mycolyltransferase Ag85C inhibitors of Mycobacterium tuberculosis H37Rv via virtual high throughput screening and binding free energy studies
J. Mol. Graph. Model.
98
107584
2020
Mycobacterium tuberculosis (P9WQP3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQP3), Mycobacterium tuberculosis H37Rv