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Information on EC 1.3.99.28 - phytoene desaturase (neurosporene-forming)

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IUBMB Comments
This enzyme is involved in carotenoid biosynthesis and catalyses up to three desaturation steps (cf. EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)], EC 1.3.99.30 [phytoene desaturase (3,4-didehydrolycopene-forming)], EC 1.3.99.31 [phytoene desaturase (lycopene-forming)]). The enzyme is activated by FAD. NAD+, NADP+ or ATP show no activating effect .
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
3-step phytoene desaturase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
15-cis-phytoene + 3 acceptor = all-trans-neurosporene + 3 reduced acceptor
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15-cis-phytoene + acceptor = all-trans-phytofluene + reduced acceptor
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all-trans-phytofluene + acceptor = all-trans-zeta-carotene + reduced acceptor
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all-trans-zeta-carotene + acceptor = all-trans-neurosporene + reduced acceptor
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