Reference on EC 1.14.14.25 - cholesterol 24-hydroxylase and Organism(s) Mus musculus and UniProt Accession Q9WVK8
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
topREF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Russell, D.W.
Oxysterol biosynthetic enzymes
Biochim. Biophys. Acta
1529
126-135
2000
Mus musculus (Q9WVK8), Homo sapiens (Q9Y6A2)
Lund, E.G.; Xie, C.; Kotti, T.; Turley, S.D.; Dietschy, J.M.; Russell, D.W.
Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover
J. Biol. Chem.
278
22980-22988
2003
Mus musculus
Lund, E.G.; Guileyardo, J.M.; Russell, D.W.
cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
Proc. Natl. Acad. Sci. USA
96
7238-7243
1999
Homo sapiens (Q9Y6A2), Homo sapiens, Mus musculus (Q9WVK8), Mus musculus
Luetjohann, D.
Cholesterol metabolism in the brain: importance of 24S-hydroxylation
Acta Neurol. Scand.
114 (Suppl. 185)
33-42
2006
Homo sapiens, Mus musculus, Sus scrofa
Kotti, T.J.; Ramirez, D.M.; Pfeiffer, B.E.; Huber, K.M.; Russell, D.W.
Brain cholesterol turnover required for geranylgeraniol production and learning in mice
Proc. Natl. Acad. Sci. USA
103
3869-3874
2006
Mus musculus
Ramirez, D.M.; Andersson, S.; Russell, D.W.
Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain
J. Comp. Neurol.
507
1676-1693
2008
Mus musculus
Russell, D.W.; Halford, R.W.; Ramirez, D.M.; Shah, R.; Kotti, T.
Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain
Annu. Rev. Biochem.
78
1017-1040
2009
Bos taurus, Canis lupus familiaris, Cavia porcellus, Danio rerio (A5WWJ0), Equus caballus, Equus sp., Gallus gallus, Homo sapiens, Macaca mulatta, Mus musculus, Ornithorhynchus anatinus, Oryctolagus cuniculus, Pan troglodytes, Rattus norvegicus, Xenopus laevis (Q7SYY2)
Shafaati, M.; O'Driscoll, R.; Bjoerkhem, I.; Meaney, S.
Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors
Biochem. Biophys. Res. Commun.
378
689-694
2009
Homo sapiens, Mus musculus, Mus musculus C57B6-J
Shafaati, M.; Mast, N.; Beck, O.; Nayef, R.; Heo, G.Y.; Bjoerkhem-Bergman, L.; Lutjohann, D.; Bjoerkhem, I.; Pikuleva, I.A.
The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase (CYP46A1) in vitro and in vivo
J. Lipid Res.
51
318-323
2010
Homo sapiens, Mus musculus
Martin, M.G.; Perga, S.; Trovo, L.; Rasola, A.; Holm, P.; Rantamaeki, T.; Harkany, T.; Castren, E.; Chiara, F.; Dotti, C.G.
Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro
Mol. Biol. Cell
19
2101-2112
2008
Mus musculus, Rattus norvegicus
Hudry, E.; Van Dam, D.; Kulik, W.; De Deyn, P.P.; Stet, F.S.; Ahouansou, O.; Benraiss, A.; Delacourte, A.; Bougneres, P.; Aubourg, P.; Cartier, N.
Adeno-associated Virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimers disease
Mol. Ther.
18
44-53
2010
Homo sapiens, Mus musculus, Mus musculus APP23
Halford, R.W.; Russell, D.W.
Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimers disease, but does extend lifespan
Proc. Natl. Acad. Sci. USA
106
3502-3506
2009
Mus musculus
Boussicault, L.; Alves, S.; Lamaziere, A.; Planques, A.; Heck, N.; Moumne, L.; Despres, G.; Bolte, S.; Hu, A.; Pages, C.; Galvan, L.; Piguet, F.; Aubourg, P.; Cartier, N.; Caboche, J.; Betuing, S.
CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntingtons disease
Brain
139
953-970
2016
Homo sapiens (Q9Y6A2), Homo sapiens, Mus musculus (Q9WVK8), Mus musculus, Mus musculus C57BL/6 (Q9WVK8)
