Any feedback?
Information on EC 1.1.99.13 - glucoside 3-dehydrogenase (acceptor)
for references in articles please use BRENDA:EC1.1.99.13Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
1.1.99.13 glucoside 3-dehydrogenase (acceptor)IUBMB Comments
The enzymes from members of the Rhizobiaceae family (such as Agrobacterium tumefaciens) act on disaccharides that contain a glucose moiety at the non-reducing end, such as sucrose, trehalose, leucrose, palatinose, trehalulose, and maltitol, forming the respective 3'-keto derivatives. cf. EC 1.1.2.11, glucoside 3-dehydrogenase (cytochrome c).
Specify your search results
Word Map
- 1.1.99.13
-
3-keto
- halomonas
- validoxylamine
- d-glucose
- saccharophilum
- faecium
- ferricyanide
-
flavobacterium
-
sphingobacterium
- 2,6-dichlorophenolindophenol
- hg2cl2
- pyranose
- phenazine
- tumefaciens
- agrobacterium
-
rhizobium
-
hydroxy
-
electrode
-
saccharide
-
cctcc
- flavin
- fad
- analysis
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
Synonyms
glucoside 3-dehydrogenase, d-glucoside 3-dehydrogenase, glucose 3-dehydrogenase, 
more
topPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
D-aldohexopyranoside dehydrogenase
-
-
ambiguous
-
D-aldohexoside:(acceptor) 3-oxidoreductase
-
-
-
-
D-glucoside 3-dehydrogenase
G3DH
glucose 3-dehydrogenase
glucoside 3-dehydrogenase
thuA
-
-
-
-
thuB
-
-
-
-
D-glucoside 3-dehydrogenase
-
-
ambiguous
-
glucoside 3-dehydrogenase
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
oxidation
redox reaction
-
-
-
-
reduction
-
-
-
-
oxidation
-
-
-
-
oxidation
-
oxidation of the C-3 hydroxyl group of the glucosides and converting them to corresponding 3-ketoglucosides. The Enzyme acts on D-Glucose, D-galactose, D-glycosides and galactosides
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYSTEMATIC NAME
IUBMB Comments
D-aldohexoside:acceptor 3-oxidoreductase
The enzymes from members of the Rhizobiaceae family (such as Agrobacterium tumefaciens) act on disaccharides that contain a glucose moiety at the non-reducing end, such as sucrose, trehalose, leucrose, palatinose, trehalulose, and maltitol, forming the respective 3'-keto derivatives. cf. EC 1.1.2.11, glucoside 3-dehydrogenase (cytochrome c).
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CAS REGISTRY NUMBER
COMMENTARY
9031-74-7
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-deoxy-D-galactose + acceptor
2-deoxy-3-dehydro-D-galactose + reduced acceptor
-
-
-
-
?
2-deoxy-D-glucose + 2,6-dichlorophenolindophenol
3-dehydro-2-deoxy-D-glucose + reduced 2,6-dichlorophenolindophenol
2-deoxy-D-glucose + acceptor
2-deoxy-3-dehydro-D-glucose + reduced acceptor
-
-
-
-
?
alpha-methyl-D-glucoside + 2,6-dichlorophenolindophenol
methyl 3-dehydro-alpha-D-glucoside + reduced 2,6-dichlorophenolindophenol
beta-methyl-D-glucoside + acceptor
3-keto-beta-methyl-D-glucoside + reduced acceptor
-
-
-
?
cellobiose + 2,6-dichlorophenolindophenol
4-O-beta-D-xylo-hexopyranosyl-3-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
D-fructose + 2,6-dichlorophenolindophenol
?
-
10.8% activity compared to D-glucose
-
-
?
D-galactose + 2,6-dichlorophenolindophenol
3-dehydro-D-galactose + 2,6-dichlorophenolindophenol
D-galactosides + acceptor
3-ketogalactosides + reduced acceptor
-
-
-
?
D-glucosamine + acceptor
3-dehydro-D-glucosamine + reduced acceptor
-
-
-
-
?
D-glucose + 2,6-dichlorophenolindophenol
2-dehydro-D-glucose + reduced 2,6-dichlorophenolindophenol
D-glucose + 2,6-dichlorophenolindophenol
3-dehydro-D-glucose + reduced 2,6-dichlorophenolindophenol
100% activity
-
-
?
D-glucose + acceptor
3-dehydro-D-glucose + reduced acceptor
-
-
-
-
?
D-glucosides + acceptor
3-ketoglucosides + reduced acceptor
-
react more rapidly than galactosides, aldopentoses and methylpentoses are no substrates
-
?
D-mannose + 2,6-dichlorophenolindophenol
3-dehydro-D-mannose + reduced 2,6-dichlorophenolindophenol
2.3% activity compared to D-glucose
-
-
?
D-mannose + acceptor
3-dehydro-D-mannose + reduced acceptor
-
-
-
-
?
isomaltose + 2,6-dichlorophenolindophenol
6-O-alpha-D-xylo-hexopyranosyl-4-ulose-alpha-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
lactose + 2,6-dichlorophenolindophenol
4-O-beta-D-xylo-hexopyranosyl-4-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
maltose + 2,6-dichlorophenolindophenol
4-O-alpha-D-ribo-hexopyranosyl-3-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
methyl-beta-thiogalactose + acceptor
3-dehydro-methyl-beta-D-thiogalactose + reduced acceptor
-
-
-
-
?
N-p-nitrophenylvalidamine + 2,6-dichlorophenolindophenol
N-p-nitrophenyl-3-ketovalidamine + reduced 2,6-dichlorophenolindophenol
-
-
-
?
p-nitrophenyl 1-thio-beta-D-glucoside + acceptor
p-nitrophenyl-1-thio-3-dehydro-beta-D-glucoside + reduced acceptor
-
-
-
-
?
p-nitrophenyl alpha-D-glucoside + acceptor
p-nitrophenyl-3-dehydro-alpha-D-glucoside + reduced acceptor
-
-
-
-
?
sucrose + 2,6-dichlorophenolindophenol
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced 2,6-dichlorophenolindophenol
TDP-glucose + acceptor
TDT-3-dehydro-D-glucose + reduced acceptor
-
-
-
-
?
trehalose + 2,6-dichlorophenolindophenol
?
-
63.8% activity compared to D-glucose
-
-
?
trehalose + 2,6-dichlorophenolindophenol
? + reduced 2,6-dichlorophenolindophenol
141.2% activity compared to D-glucose
-
-
?
validamine + 2,6-dichlorophenolindophenol
?
-
98.5% activity compared to D-glucose
-
-
?
validamycin A + 2,6-dichlorophenolindophenol
?
-
28.1% activity compared to D-glucose
-
-
?
validoxylamine A + 2,6-dichlorophenolindophenol
?
-
58.6% activity compared to D-glucose
-
-
?
valienamine + 2,6-dichlorophenolindophenol
?
-
4.4% activity compared to D-glucose
-
-
?
1,5-anhydro-D-glucitol + acceptor
1,3,5-dehydro-D-glucitol + reduced acceptor
-
-
-
?
1,5-anhydro-D-glucitol + acceptor
1,3,5-dehydro-D-glucitol + reduced acceptor
-
-
-
?
1,5-anhydro-D-glucitol + acceptor
1,3,5-dehydro-D-glucitol + reduced acceptor
-
-
-
-
?
1,5-anhydro-D-glucitol + acceptor
1,3,5-dehydro-D-glucitol + reduced acceptor
-
ferricyanide as acceptor
ferricyanide as electron acceptor
?
1,5-anhydro-D-glucitol + acceptor
1,3,5-dehydro-D-glucitol + reduced acceptor
-
-
-
-
?
1,5-anhydro-D-glucitol + acceptor
1,3,5-dehydro-D-glucitol + reduced acceptor
-
ferricyanide as acceptor
ferricyanide as electron acceptor
?
2-deoxy-D-glucose + 2,6-dichlorophenolindophenol
3-dehydro-2-deoxy-D-glucose + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
2-deoxy-D-glucose + 2,6-dichlorophenolindophenol
3-dehydro-2-deoxy-D-glucose + reduced 2,6-dichlorophenolindophenol
-
21.5% activity compared to D-glucose
-
-
?
2-deoxy-D-glucose + 2,6-dichlorophenolindophenol
3-dehydro-2-deoxy-D-glucose + reduced 2,6-dichlorophenolindophenol
43.2% activity compared to D-glucose
-
-
?
2-deoxy-D-glucose + 2,6-dichlorophenolindophenol
3-dehydro-2-deoxy-D-glucose + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
2-deoxy-D-glucose + 2,6-dichlorophenolindophenol
3-dehydro-2-deoxy-D-glucose + reduced 2,6-dichlorophenolindophenol
43.2% activity compared to D-glucose
-
-
?
alpha-methyl-D-glucoside + 2,6-dichlorophenolindophenol
methyl 3-dehydro-alpha-D-glucoside + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
alpha-methyl-D-glucoside + 2,6-dichlorophenolindophenol
methyl 3-dehydro-alpha-D-glucoside + reduced 2,6-dichlorophenolindophenol
-
96% activity compared to D-glucose
-
-
?
alpha-methyl-D-glucoside + 2,6-dichlorophenolindophenol
methyl 3-dehydro-alpha-D-glucoside + reduced 2,6-dichlorophenolindophenol
98.8% activity compared to D-glucose
-
-
?
alpha-methyl-D-glucoside + 2,6-dichlorophenolindophenol
methyl 3-dehydro-alpha-D-glucoside + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
alpha-methyl-D-glucoside + 2,6-dichlorophenolindophenol
methyl 3-dehydro-alpha-D-glucoside + reduced 2,6-dichlorophenolindophenol
98.8% activity compared to D-glucose
-
-
?
alpha-methyl-D-glucoside + acceptor
3-keto-alpha-methyl-glucoside + reduced acceptor
-
-
-
?
alpha-methyl-D-glucoside + acceptor
3-keto-alpha-methyl-glucoside + reduced acceptor
-
-
-
?
alpha-methyl-D-glucoside + acceptor
3-keto-alpha-methyl-glucoside + reduced acceptor
-
-
-
?
alpha-methyl-D-glucoside + acceptor
3-keto-alpha-methyl-glucoside + reduced acceptor
-
-
-
?
cellobiose + 2,6-dichlorophenolindophenol
4-O-beta-D-xylo-hexopyranosyl-3-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
105.9% activity compared to D-glucose
-
-
?
cellobiose + 2,6-dichlorophenolindophenol
4-O-beta-D-xylo-hexopyranosyl-3-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
-
97.4% activity compared to D-glucose
-
-
?
cellobiose + 2,6-dichlorophenolindophenol
4-O-beta-D-xylo-hexopyranosyl-3-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
105.9% activity compared to D-glucose
-
-
?
D-fructose + 2,6-dichlorophenolindophenol
? + reduced 2,6-dichlorophenolindophenol
36.5% activity compared to D-glucose
-
-
?
D-fructose + 2,6-dichlorophenolindophenol
? + reduced 2,6-dichlorophenolindophenol
36.5% activity compared to D-glucose
-
-
?
D-galactose + 2,6-dichlorophenolindophenol
3-dehydro-D-galactose + 2,6-dichlorophenolindophenol
-
63.5% activity compared to D-glucose
-
-
?
D-galactose + 2,6-dichlorophenolindophenol
3-dehydro-D-galactose + 2,6-dichlorophenolindophenol
76.5% activity compared to D-glucose
-
-
?
D-galactose + acceptor
3-dehydro-D-galactose + reduced acceptor
-
-
-
-
?
D-galactose + acceptor
3-dehydro-D-galactose + reduced acceptor
-
-
-
-
?
D-galactose + acceptor
3-dehydro-D-galactose + reduced acceptor
-
-
-
-
?
D-glucose + 2,6-dichlorophenolindophenol
2-dehydro-D-glucose + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
D-glucose + 2,6-dichlorophenolindophenol
2-dehydro-D-glucose + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
D-glucose + acceptor
3-ketoglucose + reduced acceptor
-
inducer of glucose 3-dehydrogenase
-
?
D-glucose + acceptor
3-ketoglucose + reduced acceptor
-
inducer of glucose 3-dehydrogenase
-
?
D-glucose + acceptor
3-ketoglucose + reduced acceptor
-
-
D-ribohexos-3-ulose
?
D-glucose + acceptor
3-ketoglucose + reduced acceptor
-
-
-
-
?
D-glucose 1-phosphate + acceptor
3-keto-D-glucose 1-phosphate + reduced acceptor
-
-
-
?
D-glucose 1-phosphate + acceptor
3-keto-D-glucose 1-phosphate + reduced acceptor
-
not D-glucose 6-phosphate
-
?
D-xylose + 2,6-dichlorophenolindophenol
?
-
3.1% activity compared to D-glucose
-
-
?
D-xylose + 2,6-dichlorophenolindophenol
?
-
3.1% activity compared to D-glucose
-
-
?
isomaltose + 2,6-dichlorophenolindophenol
6-O-alpha-D-xylo-hexopyranosyl-4-ulose-alpha-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
109.4% activity compared to D-glucose
-
-
?
isomaltose + 2,6-dichlorophenolindophenol
6-O-alpha-D-xylo-hexopyranosyl-4-ulose-alpha-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
-
55.5% activity compared to D-glucose
-
-
?
L-arabinose + 2,6-dichlorophenolindophenol
?
-
4.4% activity compared to D-glucose
-
-
?
L-arabinose + 2,6-dichlorophenolindophenol
?
-
4.4% activity compared to D-glucose
-
-
?
lactose + 2,6-dichlorophenolindophenol
4-O-beta-D-xylo-hexopyranosyl-4-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
lactose + 2,6-dichlorophenolindophenol
4-O-beta-D-xylo-hexopyranosyl-4-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
113.5% activity compared to D-glucose
-
-
?
lactose + 2,6-dichlorophenolindophenol
4-O-beta-D-xylo-hexopyranosyl-4-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
-
89.1% activity compared to D-glucose
-
-
?
lactose + 2,6-dichlorophenolindophenol
4-O-beta-D-xylo-hexopyranosyl-4-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
maltose + 2,6-dichlorophenolindophenol
4-O-alpha-D-ribo-hexopyranosyl-3-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
123.5% activity compared to D-glucose
-
-
?
maltose + 2,6-dichlorophenolindophenol
4-O-alpha-D-ribo-hexopyranosyl-3-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
-
58% activity compared to D-glucose
-
-
?
maltose + 2,6-dichlorophenolindophenol
4-O-alpha-D-ribo-hexopyranosyl-3-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
-
58% activity compared to D-glucose
-
-
?
maltose + 2,6-dichlorophenolindophenol
4-O-alpha-D-ribo-hexopyranosyl-3-ulose-beta-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
123.5% activity compared to D-glucose
-
-
?
methyl-beta-D-glucose + acceptor
3-keto-methyl-beta-D-glucose + reduced acceptor
-
-
-
?
methyl-beta-D-glucose + acceptor
3-keto-methyl-beta-D-glucose + reduced acceptor
-
-
-
?
p-nitrophenylvalidamine + acceptor
p-nitrophenyl-3-ketovalidamine + reduced acceptor
-
-
-
?
p-nitrophenylvalidamine + acceptor
p-nitrophenyl-3-ketovalidamine + reduced acceptor
-
-
-
?
p-nitrophenylvalienamine + acceptor
p-nitrophenyl-3-ketovalienamine + reduced acceptor
-
-
-
?
p-nitrophenylvalienamine + acceptor
p-nitrophenyl-3-ketovalienamine + reduced acceptor
-
-
-
?
sucrose + 2,6-dichlorophenolindophenol
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
sucrose + 2,6-dichlorophenolindophenol
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced 2,6-dichlorophenolindophenol
-
46.5% activity compared to D-glucose
-
-
?
sucrose + 2,6-dichlorophenolindophenol
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced 2,6-dichlorophenolindophenol
96.8% activity compared to D-glucose
-
-
?
sucrose + 2,6-dichlorophenolindophenol
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
poor substrate
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
poor substrate
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
-
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
-
3-ketosucrose, alpha-D-ribo-hexopyranosyl-3-ulose-beta-fructofuranoside
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
2,6-dichlorophenolindophenol as electron acceptor
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
ferricyanide as electron acceptor
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
cytochrome c from heart muscle as electron acceptor
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
electron acceptor phenazine methosulfate
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
2,6-dichlorophenolindophenol as electron acceptor
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
electron acceptor phenazine methosulfate
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
2,6-dichlorophenolindophenol as electron acceptor
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
ferricyanide as electron acceptor
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
acts on carbohydrates of hexopyranose C-1 chair form with a hemiacetal oxygen or sulfur at C-1, an equatorial hydroxy group at C-3 and a CH2OH group at C-5, equatorial configuration at C-2 and C-4 is preferred to an axial configuration
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
cytochrome c551 as physiological H-acceptor, membrane-bound
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
electron acceptor phenazine methosulfate
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
-
-
-
?
sucrose + acceptor
3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
-
-
-
-
?
UDP-glucose + acceptor
UDP-3-dehydro-D-glucose + reduced acceptor
-
-
-
-
?
UDP-glucose + acceptor
UDP-3-dehydro-D-glucose + reduced acceptor
-
-
-
-
?
validoxylamine A + acceptor
3-ketovalidoxylamine A + reduced acceptor
-
fungicide
-
?
validoxylamine A + acceptor
3-ketovalidoxylamine A + reduced acceptor
-
fungicide
-
?
additional information
?
-
-
enzyme activity is low with L-arabinose and D-xylose, and with 3-O-methyl-D-glucose, D-mannitol, D-mannose, sucralose and D-sorbitol giving no activity
-
-
?
additional information
?
-
-
enzyme activity is low with L-arabinose and D-xylose, and with 3-O-methyl-D-glucose, D-mannitol, D-mannose, sucralose and D-sorbitol giving no activity
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
COFACTOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE