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BRENDA support

Ligand sucrose

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Basic Ligand Information

Molecular Structure
Picture of sucrose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H22O11
sucrose
CZMRCDWAGMRECN-UGDNZRGBSA-N
Synonyms:
alpha-D-glucopyranosyl-(1,2)-beta-D-fructofuranose, alpha-D-glucopyranosyl-(1,2)-beta-D-fructofuranoside, alpha-D-glucopyranosyl-(1-2)-beta-D-fructofuranose, alpha-D-glucopyranosyl-(1->2)-beta-D-fructofuranoside, beta-D-fructofuranosyl-alpha-D-glucopyranoside, saccharose, sucrose[side 1], sugar, Sugars


Show all pahtways known for Show all BRENDA pathways known for sucrose

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (82 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sucrose + O2 = ? + H2O2
show the reaction diagram
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UDPgalactose + sucrose = UDP + 6F-alpha-galactosylsucrose
show the reaction diagram
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1-kestose + 3 sucrose = 3 neokestose + H2O
show the reaction diagram
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sucrose + (1->6)-alpha-D-glucan = D-fructose + (1->6)-alpha-D-glucan containing a (1->3)-alpha-D-glucose branch
show the reaction diagram
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sucrose + (1->6)-alpha-D-glucan = D-fructose + (1->6)-alpha-D-glucan containing a (1->2)-alpha-D-glucose branch
show the reaction diagram
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[protein]-Npi-phospho-L-histidine + sucrose[side 1] = [protein]-L-histidine + sucrose 6'-phosphate[side 2]
show the reaction diagram
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beta-D-fructofuranosyl-alpha-D-glucopyranoside + H2O = beta-D-fructofuranose + alpha-D-glucopyranose
show the reaction diagram
sucrose + H2O = alpha-D-glucose + D-fructose
show the reaction diagram
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sucrose + H2O = alpha-D-glucose + beta-D-fructose
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4 1-kestose = sucrose + 1G-kestotetraose + 6G-kestotetraose + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (878 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sucrose + NAD+ = ?
show the reaction diagram
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sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor
show the reaction diagram
-
sucrose + O2 = ? + H2O2
show the reaction diagram
-
sucrose + O2 = ? + H2O2
show the reaction diagram
-
sucrose + 2,6-dichlorophenolindophenol = ? + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
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acetyl-CoA + sucrose = CoA + beta-D-fructofuranosyl 6-O-acetyl-alpha-D-glucopyranoside
show the reaction diagram
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UDP-glucose + sucrose = UDP + ?
show the reaction diagram
-
UDPgalactose + sucrose = UDP + 6F-alpha-galactosylsucrose
show the reaction diagram
-
sucrose + starch = ?
show the reaction diagram
-
sucrose = fructose + glucose
show the reaction diagram
-
sucrose + phosphate = alpha-D-glucopyranose 1-phosphate + beta-D-fructofuranose
show the reaction diagram
-
sucrose + [(1->3)-alpha-D-glucosyl]n = D-fructose + [(1->3)-alpha-D-glucosyl]n+1
show the reaction diagram
-
UDP-galactose + sucrose = UDP + loliose
show the reaction diagram
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sucrose + H2O = D-fructose + D-glucose
show the reaction diagram
sucrose + H2O = D-fructose + D-glucose
show the reaction diagram
-
sucrose + H2O = 2 D-glucose
show the reaction diagram
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sucrose + H2O = beta-D-fructose + alpha-D-glucose
show the reaction diagram
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saccharose + H2O = ?
show the reaction diagram
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sucrose + H2O = D-fructose + D-glucose
show the reaction diagram
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sucrose + H2O = D-fructose + D-glucose
show the reaction diagram
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sucrose + H2O = D-glucose + D-fructose
show the reaction diagram
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dextran + sucrose = 6G-alpha-isomaltosylsucrose + H2O
show the reaction diagram
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Galbeta(1-3)GalNAcalpha(1-)p-nitrophenyl + sucrose = ?
show the reaction diagram
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sucrose + H2O = D-fructose + D-glucose
show the reaction diagram
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sucrose + D-galactopyranose = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (77 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,1-nystose + 1,1-nystose = sucrose + 1-kestose + oligofructan DP5 + oligofructan DP6
show the reaction diagram
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dextran + H2O = sucrose
show the reaction diagram
-
4 1-kestose = sucrose + 1G-kestotetraose + 6G-kestotetraose + H2O
show the reaction diagram
-
1-kestose + H2O = D-fructose + sucrose
show the reaction diagram
-
isomaltulose = sucrose
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (35 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
in wild-type seedlings G6PD5 and G6PD6 show small (1.7- and 2fold, respectively) but significant induction by sucrose
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4% activation at 2 mM
-
activation of autocatalytical flavinylation of the enzyme at 20%
-
stimulates
-
treatment of cells with elevated sucrose levels increases DGAT activity
-
25% increase of activity
-
sucrose concentration at 10% (w/v) is the excellent levansucrase inducer
exogenous, as well as treatments like spikelet thinning, leaf cutting increase enzyme expression and enzyme activity during rice grain filling
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the fructosyl transferase activity in strain NCIB 11871 is induced only by sucrose, other sugars tested as inducers (glucose, fructose, maltose, and cellobiose) are ineffective
-
favores CGTase synthesis
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stimulate
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400 mM, 5fold increase of activity
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5%, activation to 123%
-
slight stimulation
-
direct inducer of cAMP-PKA signaling
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stimulates, stimulation pattern of MtrA is similar to that of MtrB
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maintains the activity of the enzyme in the presence of guanidine hydrochloride
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rapid activation in vivo
-
the activity of ibAGP1 promoter is sucrose inducible
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activation
-
44% activation at 3 mM
-
increases Vmax, especially in presence of cations
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cosolvent stabilizes tubulin
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is capable of enhancing lactase gene expression in starved rats when they have a sustainable thyroid hormone level
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2 M sucrose activates the enzyme 3.3fold in the absence of monovalent cations
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the production of isomaltulose with alginate-immobilized Protaminobacter rubrum at 30 °C is influenced by sucrose concentration. Isomaltulose yields above 90% in 8 h are reached in 40-65% sucrose solutions, and yields up to 82% in 24 h were obtained with 70% sucrose. At higher concentrations (75%) a significant decrease in the isomaltulose yield (42.7-55%) is observed
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activates in absence of the activator acetylglutamate
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required for full in vitro activity, at 250 mM
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Inhibitor in Enzyme-catalyzed Reactions (141 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
10% inhibition at 20%
-
20% w/v, complete irreversible inactivation
-
hypertonic
-
inhibits promoter activity
-
weak
-
E 192, 12% inhibition
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