Reference on EC 1.1.1.85 - 3-isopropylmalate dehydrogenase and Organism(s) Thermus thermophilus and UniProt Accession Q72IW9
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Onodera, K.; Moriyama, H.; Takenaka, A.; Tanaka, N.; Akutsu, N.; Muro, M.; Oshima, T.; Imada, K.; Sato, M.; Katsube, Y.
Crystallization and preliminary X-ray studies of a Bacillus subtilis and Thermus thermophilus HB8 chimeric 3-isopropylmalate dehydrogenase
J. Biochem.
109
1-2
1991
Bacillus subtilis, Thermus thermophilus
Yamada, T.; Akutsu, N.; Miyazaki, K.; Kakinuma, K.; Yoshida, M.; Oshima, T.
Purification, catalytic properties, and thermal stability of threo-Ds-3-isopropylmalate dehydrogenase coded by leuB gene from an extreme thermophile, Thermus thermophilus strain HB8
J. Biochem.
108
449-456
1990
Thermus thermophilus
Kakinuma, K.; Ozawa, K.; Fujimoto, Y.; Akutsu, N.; Oshima, T.
Stereochemistry of the decarboxylation reaction catalysed by 3-isopropylmalate dehydrogenase from the thermophilic bacterium Thermus thermophilus
J. Chem. Soc. Chem. Commun.
1989
1190-1192
1989
Thermus thermophilus
-
Katsube, Y.; Tanaka, N.; Takenaka, A.; Yamada, T.; Oshima, T.
Crystallization and preliminary X-ray data for 3-isopropylmalate dehydrogenase of Thermus thermophilus
J. Biochem.
104
679-680
1988
Thermus thermophilus
Hamasawa, K.; Kobayashi, Y.; Harada, S.; Yoda, K.; Yamasaki, M.; Tamura, G.
Molecular cloning and nucleotide sequence of the 3-isopropylmalate dehydrogenase gene of Candida utilis
J. Gen. Microbiol.
133
1089-1097
1987
Cyberlindnera jadinii, Saccharomyces cerevisiae, Thermus thermophilus
Sekiguchi, T.; Suda, M.; Sekiguchi, T.; Nosoh, Y.
Cloning and DNA homology of 3-isopropylmalate dehydrogenase genes from thermophilic bacilli
FEMS Microbiol. Lett.
36
41-45
1986
[Bacillus] caldolyticus, [Bacillus] caldotenax, Bacillus subtilis, Saccharomyces cerevisiae, Escherichia coli, Thermus thermophilus
-
Sekiguchi, T.; Ortega-Cesena, J.; Nosoh, Y.; Ohashi, S.; Tsuda, K.; Kanaya, S.
DNA and amino-acid sequences of 3-isopropylmalate dehydrogenase of Bacillus coagulans. Comparison with the enzymes of Saccharomyces cerevisiae and Thermus thermophilus
Biochim. Biophys. Acta
867
36-44
1986
Weizmannia coagulans, Bacillus subtilis, Saccharomyces cerevisiae, Thermus thermophilus
-
Tanaka, T.; Kawano, N.; Oshima, T.
Cloning of 3-isopropylmalate dehydrogenase gene of an extreme thermophile and partial purification of the gene product
Biochemistry
89
677-682
1981
Thermus thermophilus
Croft, J.E.; Love, D.R.; Bergquist, P.L.
Expression of leucine genes from an extremely thermophilic bacterium in Escherichia coli
Mol. Gen. Genet.
210
490-497
1987
Escherichia coli, Thermus thermophilus, Salmonella enterica subsp. enterica serovar Typhimurium
Wallon, G.; Kryger, G.; Lovett, S.T.; Oshima, T.; Ringe, D.; Petsko, G.A.
Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus
J. Mol. Biol.
266
1016-1031
1997
Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium, Thermus thermophilus
Dean, A.M.; Dvorak, L.
The role of glutamate 87 in the kinetic mechanism of Thermus thermophilus isopropylmalate dehydrogenase
Protein Sci.
4
2156-2167
1995
Thermus thermophilus
Suzuki, T.; Yasugi, M.; Arisaka, F.; Yamagishi, A.; Oshima, T.
Adaptation of a thermophilic enzyme, 3-isopropylmalate dehydrogenase, to low temperatures
Protein Eng.
14
85-91
2001
Thermus thermophilus
Aoshima, M.; Oshima, T.
Stabilization of Escherichia coli isopropylmalate dehydrogenase by single amino acid substitution
Protein Eng.
10
249-254
1997
Escherichia coli, Thermus thermophilus
Akanuma, S.; Qu, C.; Yamagishi, A.; Tanaka, N.; Oshima, T.
Effect of polar side chains at position 172 on thermal stability of 3-isopropylmalate dehydrogenase from Thermus thermophilus
FEBS Lett.
410
141-144
1997
Thermus thermophilus
Chen, R.; Greer, A.; Dean, A.M.
Redesigning secondary structure to invert coenzyme specificity in isopropylmalate dehydrogenase
Proc. Natl. Acad. Sci. USA
93
12171-12176
1996
Thermus thermophilus
Qu, C.; Akanuma, S.; Tanaka, N.; Moriyama, H.; Oshima, T.
Design, X-ray crystallography, molecular modelling and thermal stability studies of mutant enzymes at site 172 of 3-isopropylmalate dehydrogenase from Thermus thermophilus
Acta Crystallogr. Sect. D
57
225-232
2001
Thermus thermophilus
Wallon, G.; Yamamoto, K.; Kirino, H.; Yamagishi, A.; Lovett, S.T.; Petsko, G.A.; Oshima, T.
Purification, catalytic properties and thermostability of 3-isopropylmalate dehydrogenase from Escherichia coli
Biochim. Biophys. Acta
1337
105-112
1997
Escherichia coli, Thermus thermophilus
Hurley, J.H.; Dean, A.M.
Structure of 3-isopropylmalate dehydrogenase in complex with NAD+: ligand-induced loop closing and mechanism for cofactor specificity
Structure
2
1007-1016
1994
Thermus thermophilus
Moriyma, H.; Onodera, K.; Sakurai, M.; Tanaka, N.; Kirino-Kagawa, H.; Oshima, T.; Katsube, Y.
The crystal structures of mutated 3-isopropylmalate dehydrogenase from Thermus thermophilus HB8 and their relationship to the thermostability of the enzyme
J. Biochem.
117(2)
408-413
1995
Thermus thermophilus
-
Suzuki, T.; Yasugi, M.; Arisaka, F.; Oshima, T.; Yamagishi, A.
Cold-adaptation mechanism of mutant enzymes of 3-isopropylmalate dehydrogenase from Thermus thermophilus
Protein Eng.
15
471-476
2002
Thermus thermophilus
Watanabe, K.; Yamagishi, A.
The effects of multiple ancestral residues on the Thermus thermophilus 3-isopropylmalate dehydrogenase
FEBS Lett.
580
3867-3871
2006
Thermus thermophilus (Q5SIY4), Thermus thermophilus
Watanabe, K.; Ohkuri, T.; Yokobori, S.; Yamagishi, A.
Designing thermostable proteins: ancestral mutants of 3-isopropylmalate dehydrogenase designed by using a phylogenetic tree
J. Mol. Biol.
355
664-674
2006
Thermus thermophilus (Q5SIY4), Thermus thermophilus
Kalinina, O.V.; Gelfand, M.S.
Amino acid residues that determine functional specificity of NADP- and NAD-dependent isocitrate and isopropylmalate dehydrogenases
Proteins
64
1001-1009
2006
Acidithiobacillus ferrooxidans (Q56268), Agrobacterium tumefaciens (P24404), Arthrospira platensis (Q00412), Aspergillus niger (P87256), Azotobacter vinelandii (P96197), Bacteroides fragilis (P54354), Brassica napus (P29102), Candida maltosa (P07139), Clostridium pasteurianum (P31958), Cyberlindnera jadinii (P08791), Eremothecium gossypii (O60027), Escherichia coli (P30125), Leptospira interrogans (P24015), Mycobacterium tuberculosis variant bovis (P94929), Ogataea angusta (P34733), Saccharomyces cerevisiae (P87267), Salmonella enterica subsp. enterica serovar Typhimurium (P37412), Scheffersomyces stipitis (O94114), Thermus aquaticus (P24098), Thermus thermophilus (P61494), Thermus thermophilus (P61495), Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 (P61494), Zymoseptoria tritici (Q9Y897), [Candida] boidinii (Q01987)
Graczer, E.; Varga, A.; Hajdu, I.; Melnik, B.; Szilagyi, A.; Semisotnov, G.; Zavodszky, P.; Vas, M.
Rates of unfolding, rather than refolding, determine thermal stabilities of thermophilic, mesophilic, and psychrotrophic 3-isopropylmalate dehydrogenases
Biochemistry
46
11536-11549
2007
Thermus thermophilus (Q5SIY4)
Graczer, E.; Varga, A.; Melnik, B.; Semisotnov, G.; Zavodszky, P.; Vas, M.
Symmetrical refolding of protein domains and subunits: example of the dimeric two-domain 3-isopropylmalate dehydrogenases
Biochemistry
48
1123-1134
2009
Vibrio sp., Escherichia coli (P30125), Escherichia coli, Thermus thermophilus (Q5SIY4), Thermus thermophilus, Vibrio sp. I5
Merli, A.; Manikandan, K.; Graczer, E.; Schuldt, L.; Singh, R.K.; Zavodszky, P.; Vas, M.; Weiss, M.S.
Crystallization and preliminary X-ray diffraction analysis of various enzyme-substrate complexes of isopropylmalate dehydrogenase from Thermus thermophilus
Acta Crystallogr. Sect. F
66
738-743
2010
Thermus thermophilus (Q5SIY4), Thermus thermophilus
Suzuki, Y.; Asada, K.; Miyazaki, J.; Tomita, T.; Kuzuyama, T.; Nishiyama, M.
Enhancement of latent 3-isopropylmalate dehydrogenase activity of promiscuous homoisocitrate dehydrogenase by directed evolution
Biochem. J.
431
401-410
2010
Thermus thermophilus (Q72IW9)
Nango, E.; Yamamoto, T.; Kumasaka, T.; Eguchi, T.
Crystal structure of 3-isopropylmalate dehydrogenase in complex with NAD(+) and a designed inhibitor
Bioorg. Med. Chem.
17
7789-7794
2009
Thermus thermophilus (Q5SIY4), Thermus thermophilus
Graczer, E.; Lionne, C.; Zavodszky, P.; Chaloin, L.; Vas, M.
Transient kinetic studies reveal isomerization steps along the kinetic pathway of Thermus thermophilus 3-isopropylmalate dehydrogenase
FEBS J.
280
1764-1772
2013
Thermus thermophilus
Graczer, E.; Konarev, P.V.; Szimler, T.; Bacso, A.; Bodonyi, A.; Svergun, D.I.; Zavodszky, P.; Vas, M.
Essential role of the metal-ion in the IPM-assisted domain closure of 3-isopropylmalate dehydrogenase
FEBS Lett.
585
3297-3302
2011
Thermus thermophilus
Graczer, E.; Merli, A.; Singh, R.K.; Karuppasamy, M.; Zavodszky, P.; Weiss, M.S.; Vas, M.
Atomic level description of the domain closure in a dimeric enzyme: Thermus thermophilus 3-isopropylmalate dehydrogenase
Mol. Biosyst.
7
1646-1659
2011
Thermus thermophilus (Q5SIY4), Thermus thermophilus
Graczer, E.; Szimler, T.; Garamszegi, A.; Konarev, P.V.; Labas, A.; Olah, J.; Pallo, A.; Svergun, D.I.; Merli, A.; Zavodszky, P.; Weiss, M.S.; Vas, M.
Dual role of the active site residues of Thermus thermophilus 3-isopropylmalate dehydrogenase: chemical catalysis and domain closure
Biochemistry
55
560-574
2016
Thermus thermophilus (Q5SIY4), Thermus thermophilus
Pallo, A.; Olah, J.; Graczer, E.; Merli, A.; Zavodszky, P.; Weiss, M.S.; Vas, M.
Structural and energetic basis of isopropylmalate dehydrogenase enzyme catalysis
FEBS J.
281
5063-5076
2014
Thermus thermophilus
Graczer, E.; Pallo, A.; Olah, J.; Szimler, T.; Konarev, P.V.; Svergun, D.I.; Merli, A.; Zavodszky, P.; Weiss, M.S.; Vas, M.
Glutamate 270 plays an essential role in K+-activation and domain closure of Thermus thermophilus isopropylmalate dehydrogenase
FEBS Lett.
589
240-245
2015
Thermus thermophilus (Q5SIY4), Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q5SIY4)
Sharma, R.; Sastry, G.N.
Deciphering the dynamics of non-covalent interactions affecting thermal stability of a protein: molecular dynamics study on point mutant of Thermus thermophilus isopropylmalate dehydrogenase
PLoS ONE
10
e0144294
2015
Thermus thermophilus (Q5SIY4), Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q5SIY4)
Kotsuka, T.; Akanuma, S.; Tomuro, M.; Yamagishi, A.; Oshima, T.
Further stabilization of 3-isopropylmalate dehydrogenase of an extreme thermophile, Thermus thermophilus, by a suppressor mutation method
J. Bacteriol.
178
723-727
1996
Thermus thermophilus (P61494), Thermus thermophilus
Sharma, R.; Sagurthi, S.; Narahari Sastry, G.
Elucidating the preference of dimeric over monomeric form for thermal stability of Thermus thermophilus isopropylmalate dehydrogenase A molecular dynamics perspective
J. Mol. Graph. Model.
96
107530
2020
Thermus thermophilus (Q5SIY4), Thermus thermophilus, Thermus thermophilus ATCC 27634 (Q5SIY4)
