show all | hide all No of entries

Information on EC 1.1.1.325 - sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)

for references in articles please use BRENDA:EC1.1.1.325
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
This enzyme, isolated from the bacterium Chlorobium tepidum, catalyses the final step in the de novo synthesis of tetrahydrobiopterin from GTP. cf. EC 1.1.1.153, sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming).
Specify your search results
Select one or more organisms in this record:
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
MDSPR, sepiapterin reductase, SPR, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-threo-7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+
show the reaction diagram
(1)
-
-
-
L-threo-tetrahydrobiopterin + 2 NADP+ = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 NADPH + 2 H+
show the reaction diagram
(2)
-
-
-
PATHWAY SOURCE
PATHWAYS
Select items on the left to see more content.