Ligand 6-pyruvoyltetrahydropterin

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Basic Ligand Information

Molecular Structure
Picture of 6-pyruvoyltetrahydropterin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H11N5O3
6-pyruvoyltetrahydropterin
WBJZXBUVECZHCE-UHFFFAOYSA-N
Synonyms:
6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin, 6-pyruvoyl-5,6,7,8-tetrahydropterin, 6-pyruvoyl-tetrahydropterin, 6-pyruvoyl tetrahydropterin, pyruvoyltetrahydropterin

Show all pahtways known for Show all pathways known for 6-pyruvoyltetrahydropterin

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
6-pyruvoyltetrahydropterin + NADPH = 6-lactoyl-5,6,7,8-tetrahydropterin + NADP+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
6-pyruvoyltetrahydropterin + NADPH = 6-lactoyl-5,6,7,8-tetrahydropterin + NADP+
show the reaction diagram
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6-pyruvoyltetrahydropterin + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + triphosphate
show the reaction diagram
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6-pyruvoyltetrahydropterin = 6-carboxy-5,6,7,8-tetrahydropterin + ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glutathione disulfide + pyrimidodiazepine = 6-pyruvoyltetrahydropterin + glutathione
show the reaction diagram
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Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.002
-
pH 7.4, 37°C
0.001
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References & Links

Links to other databases for 6-pyruvoyltetrahydropterin

ChEBI
PubChem
ChEBI
PubChem