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EC 3.2.1.10 Details
EC number
3.2.1.10
Accepted name
oligo-1,6-glucosidase
Reaction
Hydrolysis of (1→6)-α-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by EC 3.2.1.1 (α-amylase), and in isomaltose
Other name(s)
limit dextrinase (erroneous), isomaltase, sucrase-isomaltase, exo-oligo-1,6-glucosidase, dextrin 6α-glucanohydrolase, α-limit dextrinase, dextrin 6-glucanohydrolase, oligosaccharide α-1,6-glucohydrolase, α-methylglucosidase
Systematic name
oligosaccharide 6-α-glucohydrolase
CAS registry number
9032-15-9
Comment
This enzyme, like EC 3.2.1.33 (amylo-α-1,6-glucosidase), can release an α-1→6-linked glucose, whereas the shortest chain that can be released by EC 3.2.1.41 (pullulanase), EC 3.2.1.142 (limit dextrinase), and EC 3.2.1.68 (isoamylase) is maltose. It also hydrolyses isomaltulose (palatinose), isomaltotriose and panose, but has no action on glycogen or phosphorylase limit dextrin. The enzyme from intestinal mucosa is a single polypeptide chain that also catalyses the reaction of EC 3.2.1.48 (sucrose α-glucosidase). Differs from EC 3.2.1.33 (amylo-α-1,6-glucosidase) in its preference for short-chain substrates and in its not requiring the 6-glucosylated residue to be at a branch point, i.e. linked at both C-1 and C-4.
History
created 1961, modified 2000, modified 2013
EC Tree
3.2.1.5 created 1961, deleted 1964
3.2.1.9 created 1961, deleted 1972
3.2.1.12 created 1961, deleted 1976
3.2.1.13 created 1961, deleted 1976
3.2.1.16 created 1961, deleted 1972
3.2.1.19 created 1961, deleted 1978
3.2.1.27 created 1961, deleted 1972
3.2.1.29 created 1961, deleted 1972
3.2.1.30 created 1961, deleted 1992
3.2.1.34 created 1965, deleted 1972
3.2.1.69 created 1972, deleted 1976
3.2.1.79 created 1972, deleted 1976
3.2.1.90 created 1976, deleted 2001
3.2.1.138 created 1992, deleted 2003
3.2.1.148 created 1972 as EC 3.3.1.3, transferred 2001 to EC 3.2.1.148, deleted 2004