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EC 2.4.1.182 Details
EC number
2.4.1.182
Accepted name
lipid-A-disaccharide synthase
Reaction
a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-α-D-glucosamine + a lipid X = UDP + a lipid A disaccharide
Other name(s)
lpxB (gene name), UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-β-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase (incorrect)
Systematic name
UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-α-D-glucosamine:2-N,3-O-bis[(3R)-3-hydroxyacyl]-α-D-glucosamine 1-phosphate 2-N,3-O-bis[(3R)-3-hydroxyacyl]-α-D-glucosaminyltransferase
CAS registry number
105843-81-0
Comment
Involved with EC 2.3.1.129 (acyl-[acyl-carrier-protein]—UDP-N-acetylglucosamine O-acyltransferase) and EC 2.7.1.130 (tetraacyldisaccharide 4′-kinase) in the biosynthesis of the phosphorylated glycolipid, lipid A, in the outer membrane of Gram-negative bacteria.
History
created 1990, modified 2021
EC Tree
2.4.1.3 created 1961, deleted 1972
2.4.1.6 created 1961, deleted 1972
2.4.1.42 created 1972, deleted 1984
2.4.1.51 created 1972, deleted 1984
2.4.1.55 created 1972, deleted 1982
2.4.1.59 created 1972, deleted 1984
2.4.1.61 created 1972, deleted 1984
2.4.1.72 created 1972, deleted 1976
2.4.1.75 created 1976, deleted 2005
2.4.1.76 created 1976, deleted 1984
2.4.1.77 created 1976, deleted 1984
2.4.1.84 created 1976, deleted 1984
2.4.1.89 created 1976, deleted 1984
2.4.1.93 created 1976, deleted 2004
2.4.1.98 created 1980, deleted 1984
2.4.1.107 created 1983, deleted 1984
2.4.1.108 created 1983, deleted 1984
2.4.1.124 created 1984, deleted 2002
2.4.1.151 created 1984, deleted 2002
2.4.1.169 created 1989, deleted 2003
2.4.1.200 created 1992, deleted 2004
2.4.1.204 created 1992, deleted 2003
2.4.1.233 created 2004, deleted 2005