2.3.1.277: 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate synthase

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For detailed information about 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate synthase, go to the full flat file.

Reaction

a medium-chain 3-oxoacyl-[acyl-carrier protein]

2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate

Synonyms

afsA, barX, scbA

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.277 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate synthase

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Results	in table
4	AA Sequence
1	Cloned(Commentary)
4	General Information
1	Inhibitors
1	KM Value [mM]
1	Metals/Ions
2	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
6	Organism
3	Pathway
2	pH Optimum
1	Purification (Commentary)
1	Reaction
6	Reference
12	Substrates and Products (Substrate)
2	Subunits
9	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Turnover Number [1/s]

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Reference on EC 2.3.1.277 - 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate synthase

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746281

Kato, J.; Funa, N.; Watanabe, H.; Ohnishi, Y.; Horinouchi, S.

Biosynthesis of gamma-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces

Proc. Natl. Acad. Sci. USA

104

2378-2383

2007

Streptomyces griseus (P18394), Streptomyces griseus IFO13350 (P18394)

750936

Horinouchi, S.; Suzuki, H.; Nishiyama, M.; Beppu, T.

Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis

J. Bacteriol.

171

1206-1210

1989

Streptomyces griseus (P18394)

2492509

751495

Hsiao, N.; S�ding, J.; Linke, D.; Lange, C.; Hertweck, C.; Wohlleben, W.; Takano, E.

ScbA from Streptomyces coelicolor A3(2) has homology to fatty acid synthases and is able to synthesize gamma-butyrolactones

Microbiology

153

1394-1404

2007

Streptomyces coelicolor (Q7AKF0), Streptomyces coelicolor A3(2) (Q7AKF0)

17464053

751498

Lee, Y.; Kitani, S.; Nihira, T.

Null mutation analysis of an afsA-family gene, barX, that is involved in biosynthesis of the gamma-butyrolactone autoregulator in Streptomyces virginiae

Microbiology

156

206-210

2010

Streptomyces virginiae (O24738)

19778967