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Information on EC 2.3.1.277 - 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate synthase

for references in articles please use BRENDA:EC2.3.1.277

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IUBMB Comments

The enzyme catalyses the first committed step in the biosynthesis of γ-butyrolactone autoregulators that control secondary metabolism and morphological development in Streptomyces bacteria.

The expected taxonomic range for this enzyme is: Streptomyces
Reaction Schemes
a medium-chain 3-oxoacyl-[acyl-carrier protein]
+
=
2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate
+

Synonyms
afsA, barX, scbA, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a medium-chain 3-oxoacyl-[acyl-carrier protein] + glycerone phosphate = 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate + a holo-[acyl-carrier protein]
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -, -
Highest Expressing Human Cell Lines
Cell Line Links Gene Links