1.5.1.48: 2-methyl-1-pyrroline reductase

This is an abbreviated version!
For detailed information about 2-methyl-1-pyrroline reductase, go to the full flat file.

Reaction

Synonyms

(R)-imine reductase, (R)-IRED, PlRIR

ECTree

     1 Oxidoreductases

         1.5 Acting on the CH-NH group of donors

             1.5.1 With NAD⁺ or NADP⁺ as acceptor

                1.5.1.48 2-methyl-1-pyrroline reductase

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Results	in table
2	Activating Compound
3	AA Sequence
1	Application
2	Cloned(Commentary)
3	Cofactor
1	General Information
10	Inhibitors
12	kcat/KM [mM/s]
13	KM Value [mM]
2	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
5	Organism
16	PDB ID
4	pH Optimum
2	pH Range
3	Protein Variants
2	Purification (Commentary)
1	Reaction
5	Reference
2	Specific Activity [micromol/min/mg]
54	Substrates and Products (Substrate)
2	Subunits
5	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
11	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 1.5.1.48 - 2-methyl-1-pyrroline reductase

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kcat/KM VALUE [1/mMs^-1]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1.22

1-methyl-3,4-dihydroisoquinoline

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

1.58

2,3,3-trimethylindolenine

Paenibacillus lactis

-

recombinant enzyme, pH 7.0, 30°C

742293

0.187

2-methyl-1-pyrroline

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

2.195

2-methyl-3,4-dihydroisoquinolin-2-ium

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

0.447

3,4-dihydroisoquinoline

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

0.25

6-(4-methoxyphenyl)-2,3,4,5-tetrahydropyridine

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

1.33

6-(prop-1-en-2-yl)-2,3,4,5-tetrahydropyridine

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

2.64

6-(thiophen-2-yl)-2,3,4,5-tetrahydropyridine

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

0.0139

6-cyclohexyl-2,3,4,5-tetrahydropyridine

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

11.4

6-methyl-2,3,4,5-tetrahydropyridine

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

0.698

6-phenyl-2,3,4,5-tetrahydropyridine

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291

5.76

6-propyl-2,3,4,5-tetrahydropyridine

Streptomyces sp. GF3587

M4ZRJ3

recombinant enzyme, pH and temperature not specified in the publication

742291