1.5.1.48: 2-methyl-1-pyrroline reductase
This is an abbreviated version!
For detailed information about 2-methyl-1-pyrroline reductase, go to the full flat file.
Reaction
Synonyms
(R)-imine reductase, (R)-IRED, PlRIR
ECTree
1.5.1.48 2-methyl-1-pyrroline reductaseAdvanced search results
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Natural Substrates Products on EC 1.5.1.48 - 2-methyl-1-pyrroline reductase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-methyl-1-pyrroline + NADPH + H+
(R)-2-methylpyrrolidine + (S)-2-methylpyrrolidine + NADP+
2-methyl-1-pyrroline + NADPH + H+
(R)-2-methylpyrrolidine + (S)-2-methylpyrrolidine + NADP+
-
-
the enzyme produces 27.5 mM (S)-2-methylpyrrolidine (92.3% e.e.) from 30 mM 2-methyl-1-pyrroline at 92.3% conversion in the presence of 2% (w/v) L-glucose after 72 h incubation, the enzyme produces 91 mM (R)-2-methylpyrrolidine with 99.2% e.e. and 27.5 mM (S)-2-methylpyrrolidine (92.3% e.e.) from 100 mM 2-methyl-1-pyrroline at 9192% conversion in the presence of 2% (w/v) L-glucose, respectively, after 84 h incubation
-
?
2-methyl-1-pyrroline + NADPH + H+
(R)-2-methylpyrrolidine + (S)-2-methylpyrrolidine + NADP+
-
-
the enzyme produces 27.5 mM (S)-2-methylpyrrolidine (92.3% e.e.) from 30 mM 2-methyl-1-pyrroline at 92.3% conversion in the presence of 2% (w/v) L-glucose after 72 h incubation, the enzyme produces 91 mM (R)-2-methylpyrrolidine with 99.2% e.e. and 27.5 mM (S)-2-methylpyrrolidine (92.3% e.e.) from 100 mM 2-methyl-1-pyrroline at 9192% conversion in the presence of 2% (w/v) L-glucose, respectively, after 84 h incubation
-
?
2-methyl-1-pyrroline + NADPH + H+
(R)-2-methylpyrrolidine + NADP+
-
-
-
?
