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1.14.13.225: F-actin monooxygenase

This is an abbreviated version!
For detailed information about F-actin monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.225

Reaction

[F-actin]-L-methionine
+
NADPH
+
O2
+
H+
=
[F-actin]-L-methionine-(R)-S-oxide
+
NADP+
+
H2O

Synonyms

MICAL, MICAL-1, MICAL-2, MICAL1, Mical2, MICAL2PV, MICAL3

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.225 F-actin monooxygenase

Cloned

Cloned on EC 1.14.13.225 - F-actin monooxygenase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene MICAL3, hMICAL3FMOCH, hMICAL3FMO, and hMICAL3FMODCHELTA213,530 are cloned into the pET-28b plasmid, recombinant overexpression of His-tagged wild-type and mutant enzymes in Escherichia coli strain Rosetta 2 pLysS