1.13.11.57: gallate dioxygenase
This is an abbreviated version!
For detailed information about gallate dioxygenase, go to the full flat file.
Word Map on EC 1.13.11.57
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1.13.11.57
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4,5-dioxygenase
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protocatechuate
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sphingomonas
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paucimobilis
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syringate
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ligab
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3-o-methylgallate
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vanillate
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4,5-cleavage
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tetrahydrofolate-dependent
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o-demethylase
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tetrahydrofolate
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extradiol
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4-oxalomesaconate
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h4folate
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20-oxidases
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gibberellin
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sphingobium
- 1.13.11.57
-
4,5-dioxygenase
- protocatechuate
-
sphingomonas
- paucimobilis
- syringate
- ligab
- 3-o-methylgallate
- vanillate
-
4,5-cleavage
-
tetrahydrofolate-dependent
- o-demethylase
- tetrahydrofolate
-
extradiol
- 4-oxalomesaconate
-
h4folate
-
20-oxidases
- gibberellin
- sphingobium
Reaction
Synonyms
DesB, GA dioxygenase, GALA, gallate 3,4-dioxygenase
ECTree
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Inhibitors
Inhibitors on EC 1.13.11.57 - gallate dioxygenase
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2,2'-dipyridyl
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2 mM 2,2'-dipyridyl, a specific Fe2+-chelator, abolishes the gallate dioxygenase activity completely
H2O2
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hydrogen peroxide at 1 mM reduces the gallate dioxygenase activity to 15%, and the activity can be partially restored (50% activity of the untreated enzyme) upon addition of 10 mM ascorbate
protocatechuate
most potent inhibitor with mixed (competitive and non-competitive) inhibition profile, 49% inhibition at 5 mM
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36.6% inhibition when the inhibitor is present in 5fold excess over substrate
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complete inhibition at 1 mM, the activity is only fully recovered with Fe2+
EDTA
complete inhibition at 0.5 mM, the oxygen consumption activity after EDTA treatment is completely recovered by addition of Fe2+ (119%)